丁苯酞联合他汀类降脂药治疗急性脑梗死的疗效及安全性分析  

Efficacy and safety analysis of buterphthalin combined with statin lipid-lowering drugs in acute cerebral infarction

作　　者：常旭华 CHANG Xu-hua(Changfeng County People's Hospital,Changfeng 231199,Anhui)

机构地区：[1]长丰县人民医院肾内科,安徽长丰231199

出　　处：《安徽医专学报》2024年第1期54-56,共3页Journal of Anhui Medical College

摘　　要：目的:探讨丁苯酞联合他汀类降脂药治疗急性脑梗死的疗效及安全性。方法:选取医院收治的70例急性脑梗死患者,随机分为观察组(35例,采用丁苯酰联合他汀类降脂药以及基础治疗)和对照组(35例,采用西医常规治疗联合他汀类降脂药治疗),对比两组患者总有效率、治疗前后炎症反应状况和神经功能评分改善情况、用药不良反应发生率。结果:观察组患者治疗总有效率明显高于对照组(P<0.05),炎症反应状况和神经功能评分改善情况明显优于对照组(P<0.05);两组患者不良反应发生率的差异无统计学意义(P0.05)。结论:丁苯酰联合他汀类降脂药治疗急性脑梗死具有良好的疗效及较高的安全性。Objective:To analyze the efficacy and safety of butyphthalide and statin lipid-lowering drugs in the treatment of acute cerebral infarction.Methods:70 patients randomly divided into observation group(35 cases,using butylphthalide combined with statin lipid-lowering drugs and basic treatment)and control group(35 cases,using conventional therapy combined with statin lipid-lowering drugs),comparing the total efficiency,inflammatory response condition and improvement of neurological function scores,and the incidence of adverse reactions.Results:The total response rate of cerebral infarction patients in the observation group was significantly higher than that of the control group(P<0.05),the improvement of inflammatory response and neurological score were significantly better than that of the control group(P<0.05),and the incidence of adverse reactions in cerebral infarction patients in the two groups was not statistically significant(P>0.05).Conclusion:Good efficacy and high safety in acute cerebral infarction.

关 键 词：丁苯酞 他汀类降脂药 急性脑梗死 疗效 安全性 

分 类 号：R743.3[医药卫生—神经病学与精神病学]