早发性与晚发性结直肠癌临床特征比较及预后的分析  

Comparison of clinical features and prognosis of early-and late-onset colorectal cancer

作　　者：龙贤 王悦 简梓晴 何琼[1] Xian Long;Yue Wang;Zi-Qing Jian;Qiong He(The First Affiliated Hospital of Jinan University,Guangzhou 510630,Guangdong Province,China)

机构地区：[1]暨南大学附属第一医院,广东省广州市510630

出　　处：《世界华人消化杂志》2024年第2期116-122,共7页World Chinese Journal of Digestology

基　　金：青年科学基金项目,No.81500420;广东省自然科学基金项目,No.2015A030310114.

摘　　要：结直肠癌(colorectal cancer,CRC)是全球常见的消化系肿瘤,发病率位于世界第3,病死率位居世界第2,近年来结直肠癌总的发病率及病死率有所下降,但早发性结直肠癌(early-onset colorectal cancer,EOCRC)呈整体增长趋势.通常把<50岁诊断的结直肠癌定义为EOCRC,与晚发性结直肠癌(late-onset colorectal cancer,LOCRC)相比,其具有独特的临床特征,且预后较差.本文就EOCRC的临床特征及预后进行简要述评.Colorectal cancer is a common digestive system tumor,ranking third in incidence and second in fatality rate in the world.In recent years,the total incidence and fatality rate of colorectal cancer decrease,but early-onset colorectal cancer(EOCRC)shows an overall rising trend.Colorectal cancer diagnosed at less than 50 years of age is generally defined as EOCRC,which has unique clinical features and a poorer prognosis than late-onset colorectal cancer.This article reviews the clinical features and prognosis of EOCRC.

关 键 词：早发性结直肠癌 临床特征 预后 

分 类 号：R735.34[医药卫生—肿瘤]