过渡金属催化卤代芳烃合成苯胺类化合物的研究进展  

Recent Advances in Transition Metal-Catalyzed Synthesis of Anilines from Aryl Halides

作　　者：宋戈洋 薛东 李刚[1,2] Geyang Song;Dong Xue;Gang Li(Key Laboratory of Applied Surface and Colloid Chemistry,Ministry of Education,Xi’an 710119,China.;School of Chemistry and Chemical Engineering,Shaanxi Normal University,Xi’an 710119,China.)

机构地区：[1]应用表面与胶体化学教育部重点实验室,西安710119 [2]陕西师范大学化学化工学院,西安710119

出　　处：《大学化学》2024年第2期321-329,共9页University Chemistry

基　　金：陕西省自然科学基金面上项目(2023-JC-YB-100);中国博士后科学基金资助项目(2023M732165)。

摘　　要：苯胺类化合物是一种重要的有机中间体和基本化工原料,广泛应用于医药、农药、染料和功能材料等研究领域。发展高效、绿色的合成苯胺类化合物一直是备受关注的研究热点之一。过去数十年,过渡金属催化卤代芳烃合成苯胺类化合物的研究由于具有底物适用广泛、官能团兼容性好及高的反应选择性等优点,引起了化学家的研究兴趣与关注。本文综述了过渡金属催化卤代芳烃合成苯胺类化合物的研究进展,主要内容包括:(1)钯催化卤代芳烃合成苯胺类化合物;(2)铜催化卤代芳烃合成苯胺类化合物;(3)镍催化卤代芳烃合成苯胺类化合物。Aniline compounds are important organic intermediates and basic chemical raw materials,widely applied in research fields such as pharmaceuticals,agrochemicals,dyes,and functional materials.The development of efficient and versatile synthesis of aniline derivatives is one of the research hotspots that have been attracting much attention.In the past few decades,the study of transition metal-catalyzed synthesis of aniline derivatives from aryl halides has attracted significant attention from chemists due to its advantages of broad substrate applicability,good functional group compatibility,and high reaction selectivity.This review summarizes the research progress in transition metal-catalyzed synthesis of aniline derivatives from aryl halides,including:(1)palladium-catalyzed synthesis of aniline derivatives from aryl halides;(2)copper-catalyzed synthesis of aniline derivatives from aryl halides;(3)nickelcatalyzed synthesis of aniline derivatives from aryl halides.

关 键 词：过渡金属催化 苯胺类化合物 卤代芳烃 胺化反应 

分 类 号：G64[文化科学—高等教育学] O6[文化科学—教育学]