子宫内膜采集器获取标本满意度的多因素分析  

Multifactor analysis of the satisfaction of specimens obtained by endometrial collector

作　　者：刘婧 邵长香 王小捷 丁俐 徐锦屏 马成斌 Liu Jing;Shao Changxiang;Wang Xiaojie;Ding Li;Xu Jinping;Ma Chengbin(Department of Gynecolgoy,Shanghai Changning Maternity and Infant Health Hospital,Shanghai 200051,China;Department of Pathology,Shanghai Changning Maternity and Infant Health Hospital,Shanghai 200051,China)

机构地区：[1]上海市长宁区妇幼保健院妇科,上海200051 [2]上海市长宁区妇幼保健院病理科,上海200051

出　　处：《实用妇科内分泌电子杂志》2023年第27期8-11,共4页Electronic Journal of Practical Gynecological Endocrinology

基　　金：上海市长宁区妇幼保健院院级课题(编号2021Y-5)。

摘　　要：目的 评估影响子宫内膜采集器获取标本满意度的相关因素。方法 选取95例可疑罹患子宫内膜癌患者,在计划行宫腔镜检查术前运用子宫内膜采集器获得子宫内膜组织,制成微量组织病理切片后判断标本满意度,采用Logistic回归分析微量子宫内膜活检取样合格率的相关影响因素。结果 95例患者中,子宫内膜采集器获取标本满意组患者58例,不满意组患者37例。不满意组患者平均年龄(60.0±10.0)岁,满意组患者平均年龄(41.6±8.8)岁,不满意组患者年龄明显高于满意组(P<0.05);不满意组绝经者例数明显多于满意组(P<0.05);不满意组术前经阴道超声(TVS)下子宫内膜厚度明显薄于满意组(P<0.05)。两组孕次、产次、异常阴道出血、肿瘤病史比较,差异无统计学意义(P>0.05)。多因素Logistic回归分析显示:年龄、术前TVS下子宫内膜厚度是子宫内膜采集器获取满意标本的相关因素。结论 绝经后女性在选择应用子宫内膜采集器作为子宫内膜癌筛查方法时,子宫内膜薄会增加假阴性风险,直接行宫腔镜检查术可能是合适的选择。Objective To evaluate the related factors affecting the satisfaction of specimen acquisition by endometrial collector.Methods 95 cases of suspected endometrial cancer were selected,and endometrial tissue was obtained by using endometrial collector before planned hysteroscopy and made into microhistopathological sections to determine sample satisfaction.Logistic regression was used to analyze the relevant factors affecting the qualification rate of microendometrial biopsy.Results Among the 95 patients,58 patients were satisfied with the specimens obtained by the endometrial collector,and 37 patients were dissatisfied.The average age of patients in the dissatisfied group was(60.0±10.0) years,and the average age of patients in the satisfied group was(41.6±8.8) years,and the age of patients in the dissatisfied group was significantly higher than that in the satisfied group(P<0.05).The number of menopause cases in the dissatisfied group was significantly higher than that in the satisfied group(P<0.05).The endometrial thickness under transvaginal ultrasonography(TVS) in the dissatisfied group was significantly thinner than that in the satisfied group(P<0.05).There was no significant difference in pregnancy time,delivery time,abnormal vaginal bleeding and tumor history between the two groups(P>0.05).Multivariate Logistic regression analysis showed that age and endometrial thickness under TVS before operation were related factors for obtaining satisfactory specimens.Conclusion In postmenopausal women choosing to use endometrial collection as a screening method for endometrial cancer,thin endometrium may increase the risk of false negative,and direct hysteroscopy may be an appropriate choice.

关 键 词：标本制备 子宫内膜 绝经 

分 类 号：R737.33[医药卫生—肿瘤]