揿针“咽四穴”联合息风定声颗粒治疗儿童发声性抽动障碍肝亢风动型45例临床观察  

Clinical observation on the treatment of 45 cases of children with vocal tic disorders of hyperactivity of liver and wind-driven type by press-acupuncture of the“pharyngeal four acupoints”combined with Xifeng Dingsheng granules(息风定声颗粒)

作　　者：董逸翔 刘运军 李威 倪田楷 DONG Yixiang;LIU Yunjun;LI Wei;NI Tiankai(Department of Pediatrics of TCM,Wenzhou Hospital of Integtated TCM and Western Medicine,Wenzhou,Zhejiang,325000,China;Department of Pediatrics,Wenzhou Hospital of Integtated TCM and Western Medicine,Wenzhou,Zhejiang,325000,China)

机构地区：[1]温州市中西医结合医院中医儿科,浙江温州325000 [2]温州市中西医结合医院儿科,浙江温州325000

出　　处：《中医儿科杂志》2024年第1期75-79,共5页Journal of Pediatrics of Traditional Chinese Medicine

基　　金：温州市基础性科研项目(Y20211071)。

摘　　要：目的观察揿针“咽四穴”联合息风定声颗粒治疗儿童发声性抽动障碍(TD)肝亢风动型的临床疗效。方法选取2021年3月至2022年1月温州市中西医结合医院中医儿科门诊收治的发声性TD肝亢风动型患儿90例,按照随机数字表法分为对照组和治疗组,各45例。对照组给予盐酸硫必利片口服,治疗组予揿针刺激“咽四穴”联合息风定声颗粒口服。2组均治疗8周后,统计临床疗效、抽动症状及焦虑状态改善情况。结果对照组总有效率为75.56%(34/45),治疗组为93.33%(42/45),2组总有效率比较,差异有统计学意义(P<0.05)。治疗前2组耶鲁综合抽动严重程度量表(YGTSS)评分比较,差异无统计学意义(P>0.05),具有可比性;治疗后2组YGTSS评分均显著下降,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组降低更显著(P<0.05)。治疗前2组汉密尔顿焦虑量表(HAMA)评估情况比较,差异无统计学意义(P>0.05),具有可比性;治疗后2组HAMA评估情况均显著改善,与同组治疗前比较,差异有统计学意义(P<0.01),且治疗组改善更显著(P<0.05)。对照组总不良反应发生率为11.11%(5/45),治疗组为2.22%(1/45),2组比较,差异无统计学意义(P>0.05)。停药后,2组不良反应均逐渐自行消失。结论揿针“咽四穴”联合息风定声颗粒治疗儿童发声性TD肝亢风动型,可明显减轻患儿的抽动症状,有效改善患儿焦虑状态,疗效显著,且安全性高,值得临床推广应用。Objective To observe the clinical efficacy of press-acupuncture“pharyngeal four acupoints”com-bined with Xifeng Dingsheng granules(息风定声颗粒)in the treatment of children with vocal tic disorder(TD)of hyperactivity of liver and wind-driven type.Methods Ninety children with vocal TD of hyperactivity of liver and wind-driven type admitted to the outpatient clinic of Traditional Chinese Medicine Pediatrics Department of Wenzhou Hospital of Integtated TCM and Western Medicine between March 2021 and January 2022 were selected and divided into a control group and a treatment group according to the method of random number table,each with 45 cases.In the control group,thiabendazole hydrochloride tablets were given orally,and in the treatment group,press-acupuncture“pharyngeal four acupoints”was combined with the oral administration of Xifeng Dingsheng granules.8 weeks of treatment was given to the two groups,and the clinical efficacy,improvement of the twitching symptom and the state of anxiety were counted.The total effective rate was 75.56%(34/45)in the control group and 93.33%(42/45)in the treatment group,and the difference between the two groups was statistically significant(P<0.05).The Yale Global Tic Severity Scale(YGTSS)scores of the 2 groups before treatment were compared,and the difference was not statistically significant(P>0.05),which was comparable;the YGTSS scores of the 2 groups after treatment were significantly decreased,and the difference was statistically significant compared with that of the same group before treatment(P<0.05),and the decrease in the treatment group was more significant(P<0.05).Comparison of Hamilton Anxiety Scale(HAMA)assessment of the 2 groups before treatment,the difference was not statistically significant(P>0.05),and it was comparable.HAMA assessment of the 2 groups after treatment were significantly improved,and the difference was statistically significant compared with that of the same group before treatment(P<0.01),and the improvement of the treatment group was

关 键 词：小儿 发声性抽动障碍 肝亢风动型 揿针 咽四穴 息风定声颗粒 临床观察 

分 类 号：R749.94[医药卫生—神经病学与精神病学]