Clinical efficacy and pathological outcomes of transanal endoscopic intersphincteric resection for low rectal cancer  

作　　者：Zhi-Wen Xu Jing-Tao Zhu Hao-Yu Bai Xue-Jun Yu Qing-Qi Hong Jun You 

机构地区：[1]Department of Gastrointestinal Oncology Surgery,The First Affiliated Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen 361000,Fujian Province,China

出　　处：《World Journal of Gastrointestinal Oncology》2024年第3期933-944,共12页世界胃肠肿瘤学杂志（英文版）（电子版）

摘　　要：BACKGROUND Transanal endoscopic intersphincteric resection(ISR)surgery currently lacks sufficient clinical research and reporting.AIM To investigate the clinical effectiveness of transanal endoscopic ISR,in order to promote the clinical application and development of this technique.METHODS This study utilized a retrospective case series design.Clinical and pathological data of patients with lower rectal cancer who underwent transanal endoscopic ISR at the First Affiliated Hospital of Xiamen University between May 2018 and May 2023 were included.All patients underwent transanal endoscopic ISR as the surgical approach.We conducted this study to determine the perioperative recovery status,postoperative complications,and pathological specimen charac-teristics of this group of patients.RESULTS This study included 45 eligible patients,with no perioperative mortalities.The overall incidence of early complications was 22.22%,with a rate of 4.44%for Clavien-Dindo grade≥III events.Two patients(4.4%)developed anastomotic leakage after surgery,including one case of grade A and one case of grade B.Postoperative pathological examination confirmed negative circumferential resection margins and distal resection margins in all patients.The mean distance between the tumor lower margin and distal resection margin was found to be 2.30±0.62 cm.The transanal endoscopic ISR procedure consistently yielded high quality pathological specimens.CONCLUSION Transanal endoscopic ISR is safe,feasible,and provides a clear anatomical view.It is associated with a low incidence of postoperative complications and favorable pathological outcomes,making it worth further research and application.

关 键 词：Intersphincteric resection TRANSANAL Rectal cancer COMPLICATIONS ENDOSCOPIC 

分 类 号：R735.37[医药卫生—肿瘤]