亚麻籽油磷虾油软胶囊对高血脂模型大鼠血脂的影响  

Effect of flaxseed oil krill oil soft capsule on blood lipid in hyperlipidemia rats model

作　　者：翟磊 陈建国 田世民 张朋朋[3] 蔡祥焜 郑立新 ZHAI Lei;CHEN Jianguo;TIAN Shimin;ZHANG Pengpeng;CAI Xiangkun;ZHENG Lixin(China National Research Institute of Food and Fermentation Industries Co.Ltd.,Beijing 100015,China;CAIQTEST(Beijing)Co.Ltd.,Beijing 100123,China;Chinese Academy of Inspection and Quarantine Comprehensive Test Center,Beijing 100123,China)

机构地区：[1]中国食品发酵工业研究院有限公司,北京100015 [2]中检科(北京)测试技术有限公司,北京100123 [3]中国检验检疫科学研究院综合检测中心,北京100123

出　　处：《食品与发酵工业》2024年第5期54-58,共5页Food and Fermentation Industries

摘　　要：为研究亚麻籽油磷虾油软胶囊对高血脂的缓解功效,将50只雄性大鼠随机分为5组,高脂饲料造模7 d,经口给予大鼠不同剂量的亚麻籽油磷虾油软胶囊内容物30 d。通过检测各组大鼠血清中甘油三酯(triglyceride,TG)、总胆固醇(total cholesterol,TC)、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)和高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)指标,评价亚麻籽油磷虾油软胶囊辅助降血脂的功效。结果显示:与空白对照组比较,模型组血清中TC、TG、LDL-C均极显著升高(P<0.01),说明模型成立;与模型对照组相比,低、高剂量组大鼠TC含量显著降低(P<0.05),分别降低了13.73%和14.79%;各剂量组大鼠TG、LDL-C含量均显著降低,TG分别降低了45.87%、55.44%和64.03%,LDL-C分别降低了40.54%、26.12%和46.85%,各剂量组大鼠体重及HDL-C无显著性差异,表明亚麻籽油磷虾油软胶囊具有辅助降血脂的功效。In order to investigate the relieving effect of flaxseed oil krill oil soft capsule on hyperlipidemia,50 male rats were random-ly divided into 5 groups.The rats were fed withhigh fat diet for 7 days and orally treated with different doses of flaxseed oil krill oil soft cap-sule for 30 days.The serum triglyceride(TG),total cholesterol(TC),low density lipoprotein cholesterol(LDL-C)and high density lipo-protein cholesterol(HDL-C)in each group were detected to evaluate the efficacy of flaxseed oil krill oil soft capsule in alleviating hyper-lipidemia.The results showed as follows,compared with the blank control group,the serum TC,TG and LDL-C contentsin model group were significantly increased(P<0.01),indicating that the model was established;Compared with model blankgroup,TC content of rats in low-dose and high-dose groups was significantly decreased(P<0.05)with reduction of 13.73%and 14.79%,respectively(P<0.05).TG and LDL-C contents of rats in all dose groups were significantly decreased,TG contents were reduced by 45.87%,55.44%and 64.03%,while LDL-C contents were reduced by 40.54%,26.12%and 46.85%.Body weight and HDL-C contents of rats in all dose groups were not significantly affected.Therefore,it is concluded that flaxseed oil krill oil soft capsule had assistant hypolipidemic effect.

关 键 词：亚麻籽油 磷虾油 软胶囊 高血脂 

分 类 号：TS225.1[轻工技术与工程—粮食、油脂及植物蛋白工程]