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作 者:曹蓉 柴圆圆 钱华[1] CAO Rong;CHAI Yuanyuan;QIAN Hua(Children's Hospital of Soochow University,Suzhou 215025,China)
出 处:《中国麻风皮肤病杂志》2024年第4期267-270,共4页China Journal of Leprosy and Skin Diseases
摘 要:目的:评价595 nm PDL与1064 nm Nd:YAG激光联合治疗婴儿尿布区溃疡性血管瘤的疗效及安全性。方法:针对尿布区域溃疡性血管瘤患者,溃疡创面采用PDL治疗,光斑直径7 mm,脉宽1.5 ms,能量密度7~9 J/cm^(2),每周重复治疗1次。非溃疡部分采用PDL和1064 nm Nd:YAG激光模式联合治疗。激光参数如下,PDL采用7 mm光斑,脉宽6 ms,能量密度12 J/cm^(2),Nd:YAG脉宽45 ms,能量密度30~40 J/cm^(2),每两周进行1次。结果:共治疗32例患者,溃疡面治疗1周后,有9例患者开始愈合,治疗2周后进行随访,有28例患者溃疡面逐渐愈合。非溃疡处皮损经2~6次治疗后,29例患者皮疹消退60%以上。3例溃疡面较大者出现明显瘢痕。结论:595 nm PDL与1064 nm Nd:YAG激光联合治疗婴儿尿布区溃疡性血管瘤安全有效。Objective:To evaluate the efficacy and safety of 595 nm PDL combined with 1064 nm Nd:YAG laser in the treatment of ulcerated infantile hemangiomas in the diaper area.Methods:The patients with ulcerated infantile hemangiomas in the diaper area were treated.Ulcers were treated with PDL(spot diameter 7 mm,pulse width 1.5 ms,energy density 7-9 J/cm^(2))every week.The remaining hemangioma excluding the ulcerated portion were treated with PDL and Nd:YAG laser(PDL,spot diameter 7 mm,pulse width 6 ms,energy density 12 J/cm^(2);Nd:YAG pulse width 45 ms,energy density 30-40 J/cm^(2))at two-week intervals.Results:Thirty-two patients were collected.Ulcerative lesions in nine patients healed within one week after the first treatment and twenty-eight patients healed within two weeks following the second treatment.The remaining hemangioma in twenty-nine patients subsided by more than 60%after two to six treatments.Obvious scarring occurred in three patients with large ulcerated lesions.Conclusions:The treatment of 595 nm PDL combined 1064 nm Nd:YAG laser is effective and safe in ulcerated infantile hemangiomas in the diaper area.
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