Development of porphyrin-based fluorescent sensors and sensor arrays for saccharide recognition  

作　　者：Yubin Ding Jiaxin Wang Ruinan Wang Yongshu Xie 

机构地区：[1]Department of Chemistry,College of Sciences,Nanjing Agricultural University,Nanjing 210095,China [2]Shanghai Key Laboratory of Functional Materials Chemistry,Key Laboratory for Advanced Materials and Institute of Fine Chemicals,School of Chemistry and Molecular Engineering,East China University of Science & Technology,Shanghai 200237,China

出　　处：《Chinese Chemical Letters》2024年第2期16-23,共8页中国化学快报（英文版）

基　　金：financially supported by the National Natural Science Foundation of China(Nos.22278229,22131005 and 21904066);333 High Level Talent Project of Jiangsu Province.

摘　　要：Saccharide sensing is a very meaningful research topic as saccharides are involved in many biological activities.However,it is challenging to design molecular sensors for saccharides because this family of compounds is hydromimetic in aqueous solutions and shares a similar chemical structure.In this review,research progress in the development of porphyrin-based saccharide sensors is described with representative examples.We focus on using porphyrin as the signal reporter because porphyrins exhibit unique advantages in high chemical stability,long emission wavelength,and multiple structural modification strategies.Reported literature results have been classified into mainly two sections according to the general working principles of the porphyrin sensor molecules.In the first section,recognition unit,design strategy and sensing performance of traditional porphyrin-based selective saccharide sensors are discussed.While in the second section,development of porphyrin-based sensor arrays for pattern recognition of saccharides has been summarized.Looking through the design strategy and sensing performance of reported achievements,it is reasonable to anticipate a bright future for designing practical porphyrin-based saccharide sensors.

关 键 词：PORPHYRIN SACCHARIDE Fluorescent sensing Selective sensing Pattern recognition 

分 类 号：O657.3[理学—分析化学] TP212[理学—化学]