Cobalt-Catalyzed Difunctionalization of Styrenes via Ligand Relay Catalysis  

作　　者：Bingcheng Wang Yufeng Sun Zhan Lu 

机构地区：[1]Department of Chemistry,Zhejiang University,Hangzhou,Zhejiang,310058 China [2]College of Chemistry,Zhengzhou University,Zhengzhou,Henan,450001 China

出　　处：《Chinese Journal of Chemistry》2023年第24期3633-3638,共6页中国化学（英文版）

基　　金：Financial supports were provided by the National Key R&D Program of China(2021YFA1500200 and 2021YFF0701600);the NSFC(22271249);the Fundamental Research Funds for the Central Universities(226-2022-00224 and 226-2023-00115).

摘　　要：Here,we report a cobalt-catalyzed sequential dehydrogenative Heck silylation/hydroamination of styrenes with hydrosilane and diazo compound to access 1-amino-2-silyl compounds with excellent regioselectivity.This difunctionalization reaction could undergo smoothly using 1 mol%catalyst loading with good functional group tolerance.Not only di-and tri-substituted hydrosilanes,but also alkoxysilane is suitable,which does explore the scope of the family of 1-amino-2-silyl compounds.The ligand relay phenomenon between neutral tridentate NNN ligand and anionic NNN ligand is observed for the first time via absorption spectral analysis in this one-pot,two-step transformations.The primary mechanism has been proposed based on the control experiments.

关 键 词：Ligand relay catalysis Difunctionalization STYRENE ALKOXYSILANE HYDROAMINATION Diazo compounds 

分 类 号：O62[理学—有机化学]