HYDROAMINATION

作品数:16被引量:10H指数:2
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相关领域:理学更多>>
相关机构:中国科学院苏州大学更多>>
相关期刊:《Chinese Journal of Catalysis》《Chinese Journal of Chemistry》《Organic Chemistry Frontiers》《Frontiers of Chemical Science and Engineering》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划天津市自然科学基金更多>>
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Enantioselective biosynthesis of vicinal diamines enabled by synergistic photo/biocatalysis consisting of an ene-reductase and a green-light-excited organic dye
《Chinese Journal of Catalysis》2025年第1期223-229,共7页Fengming Shi Bin Chen Jinhai Yu Ruiqi Zhu Yu Zheng Xiaoqiang Huang 
国家自然科学基金(22277053);国家重点研发计划(2022YFA0913000);江苏省自然科学基金项目(BK20220760);南京大学卓越计划(ZYJH004)。
Vicinal diamines are key motifs widely-found in many pharmaceuticals and biologically active molecules.An appealing approach for synthesizing these molecules is the amination of enamines,but few examples have been exp...
关键词:Photobiocatalysis Vicinal diamines Asymmetric synthesis HYDROAMINATION Green light excitation 
Stereoselective Synthesis of 2-Deoxy-α-N-Glycosides from Glycals with 1,4,2-Dioxazol-5-ones
《Chinese Journal of Chemistry》2024年第18期2147-2152,共6页Zhenpeng Shen Guoyin Yin Yangyang Li 
supported by the National Natural Science Foundation of China(22122107).
The synthesis of N-glycosides has received significant attention due to their crucial role in carbohydrate chemistry.Despite considerable advancements developed in the construction of N-glycosides,methods for the ster...
关键词:2-Deoxy-α-N-glycosides Nickel catalysis STEREOSELECTIVITY GLYCALS HYDROAMINATION Amides Glycosylation Alkenes ComprehensiveSummary 
Cobalt(Ⅲ)hydride HAT mediated enantioselective intramolecular hydroamination access to chiral pyrrolidines
《Science China Chemistry》2024年第6期2002-2008,共7页Qi Meng Tao Qin Huanran Miao Ge Zhang Qian Zhang 
supported by the National Natural Science Foundation of China(22171043,22193012,221831002);the Fundamental Research Funds for the Central Universities-Excellent Youth Team Program(2412023YQ001);Ten Thousand Talents Program for generous financial support。
Enantioenriched pyrrolidines and derivatives are ubiquitous substructures in compounds of importance to medicinal and biological chemistry.Herein,we report an efficient cobalt-catalyzed intramolecular asymmetric hydro...
关键词:asymmetric catalysis radical hydroamination cobalt catalysis hydrogen atom transfer 
Recent Advances in Domino Synthesis of Fused Polycyclic N-Heterocycles Based on Intramolecular Alkyne Hydroamination under Copper Catalysis
《Chinese Journal of Chemistry》2023年第24期3751-3771,共21页Zefeng Jin Guodong Shen Xin Lv 
financial supports from the Natural Science Foundation of Zhejiang Province(LY21B020005);the National Natural Science Foundation of China(21202152).
Fused polycyclic N-heterocycles are very important scaffolds in biomedicinal chemistry and materials science.Intramolecular alkyne hydroamination is a powerful method for the construction of N-heterocycles.In the last...
关键词:Domino reactions Polycyclic N-heterocycles Fused-ring systems Intramolecular hydroamination ALKYNES Copper CYCLIZATION Synthetic methods 
Cobalt-Catalyzed Difunctionalization of Styrenes via Ligand Relay Catalysis被引量:1
《Chinese Journal of Chemistry》2023年第24期3633-3638,共6页Bingcheng Wang Yufeng Sun Zhan Lu 
Financial supports were provided by the National Key R&D Program of China(2021YFA1500200 and 2021YFF0701600);the NSFC(22271249);the Fundamental Research Funds for the Central Universities(226-2022-00224 and 226-2023-00115).
Here,we report a cobalt-catalyzed sequential dehydrogenative Heck silylation/hydroamination of styrenes with hydrosilane and diazo compound to access 1-amino-2-silyl compounds with excellent regioselectivity.This difu...
关键词:Ligand relay catalysis Difunctionalization STYRENE ALKOXYSILANE HYDROAMINATION Diazo compounds 
Asymmetric Access of γ-Amino Acids and γ-Amino Phosphonic Acid Derivatives via Copper-Catalyzed Enantioselective and Regioselective Hydroamination被引量:2
《CCS Chemistry》2022年第6期1901-1911,共11页Zhiping Yang Qingwei Du Yanxin Jiang Jun(Joelle) Wang 
the National Natural Science Foundation of China(NSFC 21971102);Guangdong Innovative Program(2019BT02Y335)for financial support.
γ-Aminobutyric acid is a major inhibitory neurotransmitter in the mammalian central nervous system that plays a substantial role in brain disorders.γ-Amino phosphonic acid is a unique surrogate of both natural and u...
关键词:asymmetric catalysis copper HYDROAMINATION γ-amino acid amino phosphine 
Cobalt-Catalyzed Intermolecular Hydroamination of Unactivated Alkenes Using NFSI as Nitrogen Source
《Chinese Journal of Chemistry》2022年第9期1066-1072,共7页Peng-Wei Sun Ze Zhang Xinyao Wang Linshan Li Yuxin Li Zhengming Li 
We declare no competing financial interests or personal relationships exiting in this article.And our work was supported by the National Natural Science Foundation of China(No.31972287).
Cheap metal(Fe,Mn,and Co)-catalyzed hydroamination of alkenes has been an attractive method for synthesis of amines because of biocompatibility of metal,excellent Markovnikov selectivity and chemoselectivity.However,m...
关键词:HYDROAMINATION ALKENES NFSI Cobalt catalysis Mild conditions 
Transition-metal-free hydroamination/defluorination/cyclization of perfluoroalkyl alkynes with amidines被引量:2
《Organic Chemistry Frontiers》2022年第1期109-116,共8页Li-Wen Sun Zi-Lun Yu Xin-Long Luo Mengtao Ma Zhi-Liang Shen Xue-Qiang Chu 
the financial support from National Natural Science Foundation of China(No.22001121 and 21772093);Natural Science Foundation of Jiangsu Province(BK20180690);National Students’Platform for Innovation and Entrepreneurship Training Program(202110291019Z);Nanjing Tech University(Start-up Grant No.39837118 and 39837146).
An efficient defluorinative net-[3+3]-cyclization strategy for the construction of perfluoroalkyl-substituted pyrimidine derivatives by using a series of perfluoroalkyl alkynes and amidines as starting materials was d...
关键词:CYCLIZATION PYRIMIDINE Transition 
Origins of catalyst-controlled enantiodivergent hydroamination of enones with pyridazinones:A computational study
《Chinese Chemical Letters》2021年第9期2769-2772,共4页Xiangwei Ren Hongli Wu Mei Zhang Wentao Zhao Genping Huang 
supported by the National Natural Science Foundation of China(Nos.22073066,21503143 and 21975179);the Natural Science Foundation of Tianjin(No.16JCQNJC05600)。
Density functional theory calculations have been performed to investigate the dipeptide phosphinecatalyzed hydroamination of enones with pyridazinones.The computations reveal that a number of the N-H...O hydrogen-bond...
关键词:Dipeptide phosphine catalyst HYDROAMINATION Mechanism Selectivity DFT calculations 
Ligand-Enabled NiH-Catalyzed Migratory Hydroamination:Chain Walking as a Strategy for Regiodivergent/Regioconvergent Remote sp^(3)C–H Amination被引量:2
《CCS Chemistry》2021年第9期2259-2268,共10页Yulong Zhang Jun He Peihong Song You Wang Shaolin Zhu 
by the National Natural Science Foundation of China(21702102 and 21772087),NSF of Jiangsu Province(BK20190281);the Six Kinds of Talent Project of Jiangsu Province(JNHB-003);the Program for High-Level Entrepreneurial and Innovative Talents Introduction of Jiangsu Province(Group Program).
Direct and positionally selective aliphatic C–H functionalization is an attractive means with which to streamline chemical synthesis.With many possible reaction sites,most traditional methods need a polar-directing g...
关键词:C–H activation AMINATION chain walking nickel regioselectivity 
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