Iron-Catalyzed Amide Bond Formation from Carboxylic Acids and Isocyanates  

作　　者：Lingjian Zi Jing Zhang 

机构地区：[1]The Institute for Advanced Studies,Wuhan University,Wuhan,Hubei,430072 China

出　　处：《Chinese Journal of Chemistry》2023年第23期3268-3274,共7页中国化学（英文版）

基　　金：the National Natural Science Foundation of China(22071185;22271224);Wuhan University startup funding for financial support.

摘　　要：We describe an iron-catalyzed amide bond formation from readily available carboxylic acids and isocyanates.This method utilizes an abundant and biocompatible iron catalyst and easily accessible starting materials,generates CO_(2) as the only byproduct,and features broad substrate scopes with good functional group compatibility.Therefore,it provides a cost-effective and practical protocol to access a diverse variety of amides.

关 键 词：Iroen Carboxylic acids AMIDES C—N bond formation REARRANGEMENT 

分 类 号：O62[理学—有机化学]