儿童眼眶占位性病变287例临床分布特征分析  

Clinical distribution feature of orbital space-occupying disease in children:a clinical study on 287 patients

作　　者：张少波 王萍 王海龙 叶飞飞 李娜 李养军 ZHANG Shaobo;WANG Ping;WANG Hailong;YE Feifei;LI Na;LI Yangjun(Department of Ophthalmology,the Second Affiliated Hospital,Air Force Military Medical University,Xi’an 710038,China;Department of Ophthalmology,Shangluo Central Hospital,Shangluo 726000,China)

机构地区：[1]空军军医大学第二附属医院眼科,西安710038 [2]商洛市中心医院眼科,商洛726000

出　　处：《中国眼耳鼻喉科杂志》2024年第2期128-133,共6页Chinese Journal of Ophthalmology and Otorhinolaryngology

摘　　要：目的探讨儿童眼眶占位性病变的病种分类和疾病分布特征。方法回顾性病例系列研究。收集2012年1月—2022年6月空军军医大学第二附属医院眼科收治入院的287例儿童眼眶占位性病变的临床资料,按照Shields分类方法,以不同性别和年龄对眼眶良、恶性疾病进行分类,分析疾病的病种分类及分布特征。结果287例儿童眼眶占位性病变中,良性病变占91.29%,恶性病变占8.71%。良性病变以囊性病变、血管性病变、神经源性肿瘤等为主,其中皮样囊肿最多见。恶性病变以肌源性肿瘤、淋巴造血系统肿瘤为主,其中横纹肌肉瘤最常见。儿童眼眶占位性病变多见于0~4岁,其中皮样囊肿、毛细血管瘤的发病率与年龄具有相关性(P<0.05)。病变性质与性别的相关性不显著,但朗格汉斯细胞组织细胞增生症、皮样囊肿、毛细血管瘤、横纹肌肉瘤等多见于男性患者。结论儿童眼眶占位性病变与成人的疾病分布不同,主要以先天性和胚胎性病变为主。良性病变以皮样囊肿为主,恶性病变以横纹肌肉瘤为主,部分疾病具有明显的年龄和性别倾向。Objective To investigate the classification and distribution features of orbital spaceoccupying diseases in children.Methods A retrospective case series study was conducted.The clinical data of 287 pediatric patients with orbital space-occupying diseases admitted to the Department of Ophthalmology at the Second Affiliated Hospital of the Air Force Military Medical University from January 2012 to June 2022 were collected.According to the Shields classification method,the benign and malignant orbital diseases were classified by gender and age,and the classification and distribution features of these diseases were analyzed.Results Among 287 children with orbital space-occupying diseases,91.29%were benign diseases and 8.71%were malignant diseases.Benign diseases mainly included cystic lesions,vascular lesions,neurogenic tumors,among which dermoid cysts were the most common.The malignant diseases mainly consisted of myogenic tumors and lymphohematopoietic system tumors,among which rhabdomyosarcoma was the most common.Orbital space-occupying lesions in children were mostly found in 0-4 years old,and the incidence rate of dermoid cysts and capillary hemangiomas was significantly correlated with age(P<0.05).The correlation between the nature of the lesion and gender is not significant,however,Langerhans cell histiocytosis,dermoid cysts,capillary hemangiomas,and rhabdomyosarcoma were more common in male patients.Conclusions The clinical distribution pattern of orbital space-occupying diseases in children is different from that observed in adults,it is mainly composed of congenital and embryonic diseases.Benign lesions are predominantly characerized by dermatoid cysts while rhabdomyosarcoma prevails among malignant cases.Certain diseases exhibit distinct age or gender predilections.

关 键 词：儿童 眼眶占位性病变 病种分类 疾病分布特征 

分 类 号：R77[医药卫生—眼科]