备孕女性HPV筛查及其疫苗接种状况调查  

Investigation of the human papillomavirus infection screening and human papillomavirus vaccination used among women expecting to be pregnant

作　　者：谢艳[1] 朱晓琴[1] 项媛媛[1] XIE Yan;ZHU Xiaoqin;XIANG Yuanyuan(Huaian Maternal and Child Health Care Hospital,Huai'an,Jiangsu Province,223002)

机构地区：[1]江苏省淮安市妇幼保健院,223002

出　　处：《中国计划生育学杂志》2024年第3期508-511,共4页Chinese Journal of Family Planning

摘　　要：目的:调查备孕女性人乳头瘤病毒(HPV)感染情况并分析HPV疫苗接种影响因素。方法:收集2022年1月-2023年1月本院健康检查的211例备孕女性宫颈样本,采用聚合酶链式反应-反向点杂交法进行HPV感染亚型分型,通过问卷调查备孕女性HPV疫苗接种情况,分析影响备孕女性HPV疫苗接种影响因素。结果:备孕女性HPV感染率为22.7%,其中高危型HPV感染率为81.25%,主要HPV感染亚型为HPV52(18.8%)、HPV16(10.4%)。HPV单一型感染率为20.6%,多重感染率为14.6%。211例HPV疫苗接种率为14.7%,文化水平低、不知道HPV疫苗是影响备孕女性HPV疫苗接种的影响因素(P<0.05)。结论:本次调查的备孕女性HPV感染率为22.7%,以HPV52、HPV16为主要感染亚型;HPV疫苗接种率较低,应加强对备孕女性相关知识宣传,提高HPV疫苗接种率。Objective:To investigate the situation of human papillomavirus(HPV)infection of women expecting to be pregnant,and to analyze the influence factors of the women with HPV vaccination used.Methods:The cervical samples of 211 women who expected to be pregnant and had received health examination in hospital from January 2022 to January 2023 were collected.Polymerase chain reaction(PCR)-reverse dot blot was used to type the HPV infected of the women.A questionnaire survey was conducted to investigate the status of the HPV vaccination used in these women,and the influencing factors of the HPV vaccination used of the women expecting to be pregnant was analyzed.Results:The overall HPV infection rate and the high-risk HPV infection rate of the women expecting to be pregnant were 22.7% and 81.25%.The subtypes of the main HPV infection of the women were HPV52(18.8%)and HPV16(10.4%).The infection rate of single HPV of the women was 20.6%,and the multiple infection rate of the women was 14.6%.The rate of HPV vaccination used of 211 women was 14.7%.The low education level and the ignorance of HPV vaccine were the influencing factors of the HPV vaccination used of the women expecting to be pregnant(P<0.05).Conclusion:The HPV infection rate of the women expecting to be pregnant was 22.7% in this survey,with the main infection subtypes of HPV52 and HPV16.The rate of HPV vaccination used of the women expecting to be pregnant is low,so the HPV-related health knowledge popularization should be strengthened,and the rate of the HPV vaccination used of the women should be increased.

关 键 词：备孕女性 人乳头瘤病毒筛查 疫苗接种 影响因素 

分 类 号：R737.33[医药卫生—肿瘤] R186[医药卫生—临床医学]