康柏西普联合视网膜激光治疗视网膜静脉阻塞继发黄斑水肿的疗效及对其睡眠的影响  

The Therapeutic Effect of Combination Therapy of Bercept and Retinal laser on Macular Edema Secondary to Retinal Vein Occlusion and Its Impact on Sleep

作　　者：李安兴 LI Anxing(Ophthalmology Department of Nan′an Hospital,Fujian Province,Nan′an 362300,China)

机构地区：[1]福建南安市医院眼科,南安362300

出　　处：《世界睡眠医学杂志》2024年第1期30-32,共3页World Journal of Sleep Medicine

摘　　要：目的:探究分析玻璃体腔注射康柏西普联合视网膜激光光凝治疗视网膜分支静脉阻塞继发黄斑水肿的疗效及对其睡眠的影响。方法:选取2022年5月至2023年5月福建南安市医院眼科收治的视网膜分支静脉阻塞继发黄斑水肿患者86例作为研究对象,按照抛币法随机分为观察组和对照组,每组43例。对照组实施视网膜激光光凝治疗,观察组实施玻璃体腔注射康柏西普联合视网膜激光光凝治疗,比较2组患者的临床疗效、治疗前后最佳矫正视力(BCVA)、黄斑中心凹视网膜厚度(CMT)和睡眠质量。结果:1)观察组临床治疗总有效率高于对照组(P<0.05);2)观察组患者治疗后的BCVA高于对照组,CMT低于对照组(P<0.05);3)观察组治疗后的睡眠质量(PSQI)评分低于对照组(P<0.05)。结论:玻璃体腔注射康柏西普联合视网膜激光光凝治疗视网膜分支静脉阻塞继发黄斑水肿可以获得较为理想的疗效,促进视力改善,还有助于提高睡眠质量,是一种切实有效的治疗方式,值得推广应用。Objective:To investigate and analyze the efficacy of intravitreal injection of Conbercept combined with retinal laser photocoagulation in the treatment of macular edema secondary to retinal branch vein occlusion and its impact on sleep.Methods:A total of 86 patients with macular edema secondary to retinal branch vein occlusion who received treatment in ophthalmology Department of Nan′an Hospital from May 2022 to May 2023 were selected as research subjects.The enrolled cases were randomly divided into observation and control groups using coin tossing method.The control group(43 patients with coin tossing as the opposite side)received retinal laser photocoagulation treatment,The observation group(43 patients with coins thrown in the front)received intravitreal injection of Conbercept combined with retinal laser photocoagulation treatment.The clinical efficacy,best corrected visual acuity(BCVA)before and after treatment,macular fovea retinal thickness(CMT),and sleep quality of the two groups of patients were observed and compared.Results:1)the total effective rate of clinical treatment in the observation group was higher than that in the control group(P<0.05);2)the BCVA of the observation group patients after treatment was higher than that of the control group,while the CMT was lower than that of the control group(P<0.05);3)the sleep quality index(PSQI)score of the observation group after treatment was lower than that of the control group(P<0.05).Conclusion:The combination of intravitreal injection of Conbercept and retinal laser photocoagulation for the treatment of macular edema secondary to retinal branch vein occlusion can achieve ideal therapeutic effects,promote visual improvement,and also help improve sleep quality.It is a practical and effective treatment method that is worth promoting and applying.

关 键 词：视网膜分支静脉阻塞 黄斑水肿 玻璃体腔注射康柏西普 视网膜激光光凝治疗 临床疗效 睡眠质量 

分 类 号：R774[医药卫生—眼科] R338.63[医药卫生—临床医学]