康复训练联合益肾达络饮和注射用甲泼尼龙琥珀酸钠对多发性硬化缓解期患者疲劳度、睡眠状态和运动功能的影响  

Effect of rehabilitation training combined with Yishen Daluo Yin and methylprednisolone sodium succinate for injection on fatigue,sleep status and motor function of multiple sclerosis at remission stage

作　　者：张晓佳 赵传清 赵丽娜 郭新伟 时伟 ZHANG Xiaojia;ZHAO Chuanqing;ZHAO Lina;GUO Xinwei;SHI Wei(Department of Nursing,Baoding No.2 Central Hospital,Baoding,Hebei 072750;Department of Neurology,Baoding No.2 Central Hospital,Baoding,Hebei 072750;Department of Neurology,Laoting County Hospital,Laoting,Hebei 063600)

机构地区：[1]河北省保定市第二中心医院护理部,河北保定072750 [2]河北省保定市第二中心医院神经内科,河北保定072750 [3]河北省乐亭县医院神经内科,河北乐亭063600

出　　处：《河北中医》2024年第3期470-473,共4页Hebei Journal of Traditional Chinese Medicine

基　　金：河北省保定市科技计划项目(编号:2241ZF202)。

摘　　要：目的观察康复训练联合益肾达络饮和注射用甲泼尼龙琥珀酸钠对多发性硬化(MS)缓解期患者疲劳度、睡眠状态和运动功能的影响。方法将90例MS缓解期患者按照随机数字表法分为2组,对照组45例予注射用甲泼尼龙琥珀酸钠、益肾达络饮治疗,康复组45例在对照组治疗基础上加康复训练。比较2组患者治疗前后疲劳度、睡眠状态和运动功能。结果2组治疗后疲劳严重程度量表(FSS)评分均较本组治疗前降低(P<0.05),且康复组降低更明显(P<0.05)。2组治疗后匹兹堡睡眠质量指数量表(PSQI)评分均较本组治疗前降低(P<0.05),且康复组降低更明显(P<0.05)。2组治疗后Lindmark感觉功能(LMAC)评分均较本组治疗前升高(P<0.05),且康复组升高更明显(P<0.05)。结论康复训练联合益肾达络饮和注射用甲泼尼龙琥珀酸钠治疗MS缓解期,能有效改善患者疲劳度、睡眠状态,提高运动功能。Objective Exploring the effects of rehabilitation training combined with Yishen Daluo Yin and methylprednisolone sodium succinate for injection on fatigue,sleep status and motor function in patients with multiple sclerosis(MS)at remission stage.Methods A tatol of 90 MS patients at remission stage were randomly divided into a control group(n=45)and treatment group(n=45).All patients received Yishen Daluo Yin and methylprednisolone sodium succinate for injection,patients in the treatment group additionally received rehabilitation training.After 8-week treatment,the status of fatigue,sleep and motor function were compared between groups.Results After treatment,the scores of fatigue severity scale(FSS)and Pittsburgh sleep quality index(PSQI)in the two groups significantly lower than those before treatment(P<0.05),but the scores of Lindmark Sensory-Motor Assessment Chart(LMAC)significantly higher(P<0.05),and the improvements in the treatment group were more pronounced(all P<0.05).Conclusions Rehabilitation training combined with Yishen Daluo Yin and methylprednisolone sodium succinate for injection can effectively improve the fatigue level,sleep status and motor function of MS patients at remission stage.

关 键 词：多发性硬化 运动疗法 中药疗法 

分 类 号：R744.51[医药卫生—神经病学与精神病学] R493.2[医药卫生—临床医学] R289.6