点状内层脉络膜病变并发脉络膜新生血管1例  

One case of patient suffering from punctate inner choroidopathy complicated with choriodal neovascularization

作　　者：王樱銮 齐艳秀[1] Wang Yingluan;Qi Yanxiu(Ophthalmology Department,the First Affiliated Hospital of Jiamusi University,Jiamusi,Heilongjiang 154000,China)

机构地区：[1]佳木斯大学附属第一医院眼科,黑龙江佳木斯154000

出　　处：《齐齐哈尔医学院学报》2024年第2期162-165,共4页Journal of Qiqihar Medical University

摘　　要：目的对1例点状内层脉络膜病变(punctate inner choroidopathy,PIC)并发脉络膜新生血管(choriodal neovascularization,CNV)进行分析,以期为临床诊疗提供思路。方法通过扫描激光眼底照相(SLO)、光学相干断层扫描(OCT)、光学相干断层扫描血管成像(OCTA)和眼底荧光素钠血管造影(FFA)等多模影像和实验室检查对本院1例PIC患者随访观察,并对其进行分析。结果利用多模式影像等早期诊断PIC,通过连续3次玻璃体腔药物注射使PIC继发的CNV消退,患者视力提升且视物变形消失。结论PIC是一种局灶炎症性疾病,累及深层视网膜及脉络膜,以多发的、边界清楚的黄白色眼底病变为特征,在SLO、OCT及FFA上的表现均提示点状内层脉络膜病变,可伴有视网膜色素上皮损害。本病主要好发于伴有中度近视的青年女性,本文报道了1例高度近视的青年男性双眼发病,单眼继发CNV。通过多模式影像和实验室检查可为临床医师提供诊断及鉴别诊断依据,尤其在区分炎性病灶与CNV上有重要意义,以期寻找更多的手段延缓疾病进展,改善患者生活质量。Objective To analyze one case of patient suffering from punctate inner choroidopathy(PIC)complicated with choriodal neovascularization(CNV),in order to provide ideas for clinical diagnosis and treatment.Methods A patient with PIC in our hospital was followed up and observed by scanning laser ophthalmoscopy(SLO),optical coherence tomography(OCT),optical coherence tomography angiography(OCTA),fundus fluorescein sodium angiography(FFA)and other multi-mode imaging and laboratory examination,and the results were analyzed.Results Multi-mode imaging was used for early diagnosis of PIC,and the secondary CNV of PIC was subsided after three consecutive intravitreal drug injections,and the visual acuity was improved and the visual deformity disappeared.Conclusions PIC is a focal inflammatory disease involving deep retina and choroid.It is characterized by multiple,well-defined yellow-white fundus disease.Manifestations on SLO,OCT and FFA all suggest punctated inner choroid lesions,which may be accompanied by retinal pigment epithelium damage.This disease mainly occurs in young women with moderate myopia.This paper reports a case of binocular disease in a young male with high myopia and secondary CNV in one eye.Multi-mode imaging and laboratory examination can provide diagnostic and differential diagnosis basis for clinicians,especially in distinguishing inflammatory lesions from CNV,in order to find more means to delay disease progression and improve patients'quality of life.

关 键 词：脉络膜疾病 多模式影像检查 脉络膜新生血管 

分 类 号：R773.4[医药卫生—眼科]