Nickel-Catalyzed Regioselective Hydrosilylation of Conjugated Dienes  

作　　者：Xiaoyu Wu Wei Liu Liqun Yang Yue Wang Tianwen Liu Yao Yuan Yan Lu Zhaoguo Zhang 

机构地区：[1]Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs,School of Chemistry and Chemical Engineering,Shanghai JiaoTong University,800 Dongchuan Road,Shanghai 200240,China [2]Joseph Black Building,The University of Edinburgh,David Brewster Road,Edinburgh,EH9 3FJ,UK

出　　处：《Chinese Journal of Chemistry》2024年第1期13-19,I0004,共8页中国化学（英文版）

摘　　要：With the increasing demand for homoallylic silanes and allylic silanes,the highly efficient and regioselective hydrosilylations of conjugated dienes are urgently needed.Herein,we developed a Ni-catalyzed regiodivergent hydrosilylation of aromatic conjugated dienes by adjusting the temperature and ligands.Under low temperature(-30℃),an eternal-ligand-free system(Ni/t-BuOk)can efficiently facilitate the 3,4-anti-Markovnikov hydrosilylation to provide homoallylic silanes via electrophilic activation process;under room temperature(25℃),a ligand-controlled system(Ni/t-BuOk/PPh3)can eventuate the 3,4-Markovnikov hydrosilylation to produce allylic silanes via Chalk-Harrod process.Both systems are compatible with various conjugated dienes and primary silanes in excellent yields andregioselectivities.

关 键 词：NICKEL-CATALYZED Regioselective hydrosilylation Conjugated dienes Electrophilic activation Homoallylic silanes 

分 类 号：O64[理学—物理化学]