腹腔镜子宫肌瘤剔除联合子宫动脉上行支阻断术治疗子对宫肌瘤患者性功能、复发率及FSH、E2与LH水平的影响  

The effect of laparoscopic myomectomy combined with uterine artery ascending branch occlusion on sexual function,recurrence,and FSH,E2,and LH levels in patients with uterine fibroids

作　　者：王文君 刘艳[1] 杨梦霞 郭红军[1] WANG Wenjun;LIU Yan;YANG Mengxia;GUO Hongjun(Department of Gynecology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan,China,450000)

机构地区：[1]郑州大学第一附属医院妇科,河南郑州450000

出　　处：《分子诊断与治疗杂志》2024年第2期352-355,360,共5页Journal of Molecular Diagnostics and Therapy

基　　金：河南省医学科技攻关计划(LHGJ2022036)。

摘　　要：目的 研究腹腔镜子宫肌瘤剔除联合子宫动脉上行支阻断术治疗子对宫肌瘤患者性功能、复发率及促卵泡激素(FSH)、雌二醇(E2)及黄体生成素(LH)水平的影响。方法 选取于2020年5月至2021年5月郑州大学第一附属医院收治的116例子宫肌瘤患者作为研究对象,依据治疗方案分为对照组(n=56,LM)和观察组(n=60,LM联合子宫动脉上行支阻断术)。比较两组围手术期指标、性激素(FSH、E2及LH)、性功能、子宫肌瘤残留率、复发率。结果 观察组手术时间长于对照组,但术中出血量少于对照组,术后排气、胃肠功能修复及住院时间均短于对照组,差异有统计学意义(P<0.05);两组术前FSH、E2及LH水平比较差异无统计学意义(P>0.05);术后3月FSH、LH均较术前升高,且观察组更高,E2均较术前降低,且观察组更低,差异有统计学意义(P<0.05);但两组术后6月时FSH、E2及LH水平比较差异均无统计学意义(P>0.05);两组术前性功能评分比较差异均无统计学意义,术后6月性功能评分均较术前改善,但两组比较,差异无统计学意义(P>0.05);观察组子宫肌瘤残留率(0.00%)、复发率(10.71%)均显著低于对照组子宫肌瘤残留率(21.43%)、复发率(3.33%),差异有统计学意义(P<0.05)。结论 LM联合子宫动脉上行支阻断术对子宫肌瘤患者卵巢功能短期内有一定影响,但可逐渐恢复至术前水平,且在改善性功能及降低患者肌瘤残留率与复发率上效果更好。Objective To study the effects of laparoscopic myomectomy combined with uterine ar-tery ascending branch occlusion on sexual function,recurrence and follicle stimulating hormone(FSH),estra-diol(E2)and luteinizing hormone(LH)levels in patients with uterine fibroids.Methods A total of 116 pa-tients with uterine fibroids admitted to the First Affiliated Hospital of Zhengzhou University from May 2020 to May 2021 were selected as the research subjects.They were divided into two groups based on the treatment plan:the control group(n=56,treated with LM)and the observation group(n=60,treated with LM com-bined with uterine artery ascending branch occlusion)according to the treatment plan.The perioperative indica-tors were compared between the two groups.Additionally,sex hormones(FSH,E2 and LH),sexual func-tion,uterine fibroid residual rate,and recurrence rate were also compared.Results The operation time of the observation group was longer than that of the control group.However,the intraoperative blood loss was less in the observation group compared to the control group.Additionally,the observation group had shorter postopera-tive exhaust,gastrointestinal function repair and hospitalization time compared to the control group,with statis-tically significant differences(P<0.05).Before the operation,there was no statistically significant difference in the levels of FSH,E2 and LH between the two groups(P>0.05).However,at 3 months after the opration,FSH and LH levels were higher than before the operation in both groups.The observation group had higher lev-els of FSH,and LH,while E2 levels were lower in the observation group.Those differences were statistically significant(P<0.05).At 6 months after operation,there was no significant difference in the levels of FSH,E2 and LH between the two groups(P>0.05).Before the operation,there was no statistically significant difference in sexual function scores between the two groups.However,at 6 months after the operation,the sexual function scores improved in both groups.There was no sta

关 键 词：腹腔镜 子宫肌瘤剔除术 子宫动脉上行支阻断术 性激素 

分 类 号：R737.33[医药卫生—肿瘤]