复发鼻咽癌的治疗:挑战与希望并存  

The treatment of recurrent nasopharyngeal carcinoma:challenges and hopes

作　　者：杨振东 王仁生[1] YANG Zhendong;WANG Rensheng(Department of Radiation Oncology,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China)

机构地区：[1]广西医科大学第一附属医院放疗科,南宁530021

出　　处：《广西医科大学学报》2024年第2期161-167,共7页Journal of Guangxi Medical University

摘　　要：尽管随着以调强放疗为主的综合治疗的广泛开展,鼻咽癌的复发率较传统二维放疗时代已经明显降低,但仍有相当一部分患者会在根治性放疗后出现复发。复发鼻咽癌(rNPC)患者的总体预后欠佳,治疗上依然面临着巨大挑战。近年来,随着新技术、新药物和新理念的发展,rNPC治疗的效果和安全性正在逐步提升,为rNPC患者带来了新的希望。为此,本文将就rNPC的治疗现状和最新进展进行归纳、梳理和分析,以期为rNPC临床治疗决策提供更多参考。With the extensive development of comprehensive therapy based on intensity modulated radiotherapy,although the recurrence rate of nasopharyngeal carcinoma has been significantly reduced compared with the traditional two-dimensional radiotherapy era,there are still a considerable number of patients who will relapse after radical radiotherapy.The overall prognosis of patients with recurrent nasopharyngeal carcinoma(rNPC)is poor,and the treatment still faces great challenges.In recent years,with the development of new technologies,new drugs and new concepts,the efficacy and safety of rNPC therapy are gradually improving,bringing new hope to rNPC patients.Therefore,this paper will summarize,sort out and analyze the current treatment status and latest progress of rNPC,so as to provide more references for clinical treatment decision-making of rNPC.

关 键 词：鼻咽癌 复发 手术治疗 放疗 化疗 免疫治疗 靶向治疗 

分 类 号：R739.63[医药卫生—肿瘤]