卒中后中枢性疼痛的诊断及治疗进展  

Progress in Diagnosis and Treatment of Central Post⁃stroke Pain

作　　者：宋淑佳 孙琛 裴丽坚[1] 徐蔚海[2] 黄宇光[1] SONG Shujia;SUN Chen;PEI Lijian;XU Weihai;HUANG Yuguang(Department of Anesthesiology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Neurology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China)

机构地区：[1]中国医学科学院北京协和医院麻醉科,北京100730 [2]中国医学科学院北京协和医院神经科,北京100730

出　　处：《协和医学杂志》2024年第2期265-271,共7页Medical Journal of Peking Union Medical College Hospital

基　　金：中央高水平医院临床科研专项(2022⁃PUMCH⁃B⁃006)。

摘　　要：卒中后中枢性疼痛(central post⁃stroke pain,CPSP)是一种发生于脑卒中后的神经病理性疼痛综合征,其特征为出现疼痛或感觉异常的身体部位由出现血管损伤的大脑区域支配。CPSP患者常伴有焦虑、抑郁等情绪障碍,导致其生活质量降低。然而目前CPSP的发生机制仍未完全阐明,以致临床诊断率不高,常用治疗手段效果欠佳。本文从CPSP的临床特征、流行病学、发生机制及治疗手段等方面展开综述,以期为CPSP的诊断及有效治疗提供参考。Central post⁃stroke pain(CPSP),a neuropathic pain syndrome occurring after a cere⁃brovascular accident,is characterized by pain or paraesthesia in the part of the body dominated by the area of the brain where blood vessels are injured.CPSP patients are often accompanied by anxiety,depression and other emotional disorders,which have a serious negative impact on patients’quality of life.However,the pathogenesis of CPSP has not been fully elucidated,the clinical diagnosis rate is not high,and the commonly used treatment methods are not effective.This article reviews the clinical features,epidemiology,pathogenesis and treatment of CPSP in order to provide reference for the elucidation of CPSP mechanism and effective treatment.

关 键 词：卒中后中枢性疼痛 神经病理性疼痛 卒中 

分 类 号：R743[医药卫生—神经病学与精神病学]