中国65岁及以上老年人肌少症和膳食多样性关系的研究  

Relationship between dietary diversity and possible sarcopenia among older adults aged 65 and over in China

作　　者：钱鸣崎 杜俏俏[1] 张文雅[1] 施蓉芳[1] 杨海珍[1] 朱小军[1] QIAN Ming-qi;DU Qiao-qiao;ZHANG Wen-ya;SHI Rong-fang;YANG Hai-zhen;ZHU Xiao-jun(Health Management Center,The Second Affiliated Hospital of Soochow University,Suzhou,Jiangsu 215004,China)

机构地区：[1]苏州大学附属第二医院健康管理中心,江苏苏州215004

出　　处：《现代预防医学》2024年第6期1005-1011,共7页Modern Preventive Medicine

摘　　要：目的探讨膳食多样性评分(DDS)和老年人肌少症之间的关系。方法利用中国老年健康与家庭幸福调查(CLHLS-HF)2018年的调查数据进行分析。采用2019年亚洲肌少症工作组(AWGS2019)制定的标准评估肌少症。通过构建四个新的DDS指标:总体膳食、动物性膳食、植物性膳食和不包含豆制品和坚果的植物性膳食评分。采用logistic回归来分析总体膳食、动物性膳食、植物性膳食和不包含豆制品和坚果的植物性膳食的DDS与可能肌少症之间的关联。并进行混杂因素调整、亚组分析及敏感性分析。结果共纳入研究对象2555名(平均年龄84.4岁),男性1244人(48.7%),女性1311人(51.3%)。可能肌少症患病率为63.9%(1632/2555),可能肌少症组的DDS明显低于非肌少症组(t=-5.216,P<0.001)。调整混杂因素后,总体膳食(OR=0.544,95%CI:0.405~0.732),动物性膳食(OR=0.613;95%CI:0.423~0.888),植物性膳食(OR=0.469;95%CI:0.321~0.684)和不包含豆制品和坚果的植物性膳食(OR=0.382;95%CI:0.206~0.709)与肌少症的发生风险均有关联。DDS越高发生可能肌少症的风险越低。敏感性分析显示相关性保持不变。亚组分析结果显示男性人群中总体膳食、动物性膳食和植物性膳食仍然与可能肌少症风险降低相关,而在女性人群中,植物性膳食以及不包含豆制品和坚果的植物性膳食与可能肌少症的风险降低有关。结论膳食多样性是老年人肌少症的保护因素,采用多样化的饮食可能会降低老年人肌少症的风险。Objective To explore the association between the dietary diversity score(DDS)and the prevalence of possible sarcopenia among the elderly.Methods We conducted this analysis utilizing the cross-sectional data from the Chinese longitudinal healthy longevity survey and happy family study(CLHLS-HF,wave 2018).A standard developed by the Asian Working Group for Sarcopenia 2019(AWGS2019)was used to assess the possibility of sarcopenia.We have constructed four new indicators of DDS as follows:total diet,animal-based diet,plant-based diet,and plant-based diet without the consumption of legume products and nuts.We used the Logistic regression analysis to evaluate the association between the DDS of the total diet,animal-based diet,plant-based diet,and plant-based diet without the intake of legume products and nuts and possible sarcopenia.These associations were statistically adjusted for a variety of potential confounders.Sensitivity analysis and subgroup analyses were performed.Results The analysis included 2555 participants(mean age of 84.4 years).1244(48.7%)were male and 1311(51.3%)were female.1632 elderly people had possible sarcopenia.DDS in the possible sarcopenia group was significantly lower than that in the non-sarcopenia group(P<0.001).In our study,we found that participants with a higher DDS of the total diet(OR=0.544,95%CI:0.405-0.732),animal-based diet(OR=0.613,95%CI:0.423-0.888),and plant-based diet(OR=0.469,95%CI:0.321-0.684)and plant-based diet without the consumption of legume products and nuts(OR=0.382,95%CI:0.206-0.709)were at a lower risk of developing sarcopenia.In sensitivity analyses,the associations remained unchanged.In subgroup analysis,total diets,animal-based diet,and plant-based diet were still associated with a reduced risk of possible sarcopenia in the male population,while plant-based diet and plant-based diet without the intake of legume products and nuts were associated with a reduced risk of possible sarcopenia in the female population.Conclusion Taking a diversified diet may reduce the ris

关 键 词：膳食多样性 肌少症 植物性膳食 老年人 

分 类 号：R153[医药卫生—营养与食品卫生学] R685[医药卫生—公共卫生与预防医学]