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作 者:王垒垒 WANG Leilei(Department of Stomatology of Xuchang Hospital of Traditional Chinese Medicine,Xuchang 461000 Henan,China)
出 处:《中国民康医学》2024年第6期64-66,70,共4页Medical Journal of Chinese People’s Health
摘 要:目的:观察Nd:YAP激光联合龈下刮治和根面平整术(SRP)治疗慢性牙周炎患者的效果。方法:选取2021年4月至2023年3月该院收治的80例慢性牙周炎患者进行前瞻性研究,采用随机数字表法将其分为研究组和对照组各40例。对照组接受SRP治疗,研究组在对照组基础上联合Nd:YAP激光治疗,比较两组临床疗效、治疗前后牙周指数[探诊深度(PD)、牙龈出血指数(BI)、菌斑指数(PLI)]、口气指标[口腔挥发性硫化物(VSCs)]水平、龈沟液炎性因子[肿瘤坏死因子-α(TNF-α)、白细胞介素-8(IL-8)、超敏C反应蛋白(hs-CRP)]水平。结果:研究组治疗总有效率为95.00%(38/40),高于对照组的77.50%(31/40),差异有统计学意义(P<0.05);治疗后,研究组PD和BI、PLI评分均低于对照组,差异有统计学意义(P<0.05);治疗后,两组VSCs水平均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05);治疗后,研究组龈沟液TNF-α、IL-8和hs-CRP水平均低于对照组,差异有统计学意义(P<0.05)。结论:Nd:YAP激光联合SRP治疗慢性牙周炎患者可降低牙周指数、口气指标水平和龈沟液炎性因子水平,效果优于单纯SRP治疗。Objective:To observe clinical effects of Nd:YAP laser combined with subgingival scaling and root planing(SRP) in treatment of patients with chronic periodontitis.Methods:A prospective study was conducted on 80 patients with chronic periodontitis admitted to the hospital from April 2021 to March 2023.They were divided into study group and control group by using the random number table method,40 cases in each group.The control group was treated with SRP,while the study group was treated with Nd:YAP laser on the basis of that of the control group.The clinical efficacy and the levels of periodontal index [probing depth(PD),gingival bleeding index(BI) and plaque index(PLI)],breath index [oral volatile sulfides(VSCs)] and gingival crevicular fluid inflammatory factors [tumor necrosis factor-α(TNF-α),interleukin-8(IL-8) and high-sensitivity C-reactive protein(hs-CRP)] were compared between the two groups before and after the treatment.Results:The total effective rate of treatment in the study group was 95.00%(38/40),which was higher than 77.50%(31/40) in the control group,and the difference was statistically significant(P<0.05).After the treatment,the scores of PD,BI and PLI in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the levels of VSCs in the two groups were lower than those before treatment,those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Further,after the treatment,the levels of TNF-α,IL-8and hs-CRP in gingival crevicular fluid in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusions:Nd:YAP laser combined with SRP in the treatment of the patients with chronic periodontitis can reduce the periodontal index and the breath index levels as well as the gingival crevicular fluid inflammatory factor levels.Moreover,it is superior to single SRP treatment.
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