Prevalence of retinal pathologies in people over 60 years:the Tehran Geriatrics Eye Study  

作　　者：Abolghasem Mortazavi Alireza Hashemi Alirerza Jamali Hassan Hashemi Mohammadreza Aghamirsalim Mehdi Khabazkhoob 

机构地区：[1]Department of Neurosurgery,Sina Hospital,Tehran University of Medical Sciences,Tehran 1416753955,Iran [2]Noor Ophthalmology Research Center,Noor Eye Hospital,Tehran 1983963113,Iran [3]Rehabilitation Research Center,Department of Optometry,School of Rehabilitation Sciences,Iran University of Medical Sciences,Tehran 1545913487,Iran [4]Noor Research Center for Ophthalmic Epidemiology,Noor Eye Hospital,Tehran 1983963113,Iran [5]Translational Ophthalmology Research Center,Tehran University of Medical Sciences,Tehran 1157715354,Iran [6]Department of Basic Sciences,School of Nursing and Midwifery,Shahid Beheshti University of Medical Sciences,Tehran 1968653111,Iran

出　　处：《International Journal of Ophthalmology(English edition)》2024年第4期721-728,共8页国际眼科杂志（英文版）

基　　金：Supported by National Institute for Medical Research Development(NIMAD)Affiliated with the Iranian Ministry of Health and Medical Education(No.963660).

摘　　要：AIM:To determine the prevalence of some retinal pathologies in people over 60y and their association with demographic and ocular factors.METHODS:A cross-sectional study was conducted in Tehran using multistage cluster sampling.After selecting subjects aged 60 and over,optometric,and ophthalmic examinations were done.For retinal examination,a 90 D lens was used and indirect ophthalmoscopy was performed after instilling tropicamide drops.Biometry was done using the IOL Master for all participants.RESULTS:Of 3791 people that were invited through cluster sampling,3310 participated in the study(response rate=82%).The prevalence of retinal pigmented epithelium(RPE)change,drusen,geographic atrophy(GA),hypertensive retinopathy(HTR),nonproliferative diabetic retinopathy(NPDR),proliferative diabetic retinopathy(PDR),choroidal neovascularization(CNV),central retinal artery occlusion(CRAO),myopic retinopathy(MR),branch retinal vein occlusion(BRVO),and central retinal vein occlusion(CRVO)was 27.42%,11.08%,4.52%,3.03%,4.05%,0.54%,0.82%,0.39%,0.20%,0.49%,and 0.19%,respectively.After removing the effect of age,the odds of NPDR were 1.68 times higher in women compared to men(P=0.014).After removing the effect of sex,the odds of drusen,RPE change,GA,CNV,BRVO,and CRVO increased with age.CONCLUSION:There is a higher prevalence of RPE change,drusen,GA,CNV and a lower prevalence of MR and CRAO in the elderly population of Tehran aged over 60y compared to global average values.Considering the correlation of most of the diseases with age and their effects on vision,attention should be paid to these diseases and the related screening programs to prevent vision impairment.

关 键 词：retinal pathologies cross-sectional study vision impairment 

分 类 号：R775[医药卫生—眼科]