瑞舒伐他汀钙片联合阿司匹林肠溶片治疗缺血性脑血管病的价值  

The value of combined administration of rosuvastatin calcium tablets and aspirin enteric-coated tablets in the treatment of ischemic cerebrovascular disease

作　　者：钱方圆 QIAN Fangyuan(Pharmacy Department,the Third Staff Hospital of Baotou Steel Group,Inner Mongolia,Baotou 014010,China)

机构地区：[1]包钢集团第三职工医院药剂科,内蒙古包头014010

出　　处：《中国医药科学》2024年第5期137-140,共4页China Medicine And Pharmacy

摘　　要：目的探讨缺血性脑血管病患者采用瑞舒伐他汀钙片联合阿司匹林肠溶片治疗的临床效果。方法选取包钢集团第三职工医院收治的218例缺血性脑血管病患者,以随机单盲法分为参照组(n=109)、分析组(n=109),参照组给予阿司匹林肠溶片治疗,分析组给予瑞舒伐他汀钙片联合阿司匹林肠溶片治疗,并比较两组临床疗效。研究起止时间为2021年1月至2022年12月。结果分析组血脂水平优于参照组,差异有统计学意义(P<0.05);分析组美国国立卫生研究院卒中量表(NIHSS)评分、Barthel指数、生活质量评价量表(SF-36)评分和治疗总有效率高于参照组,差异有统计学意义(P<0.05)。结论缺血性脑血管病患者联合使用瑞舒伐他汀钙片与阿司匹林肠溶片治疗效果确切,可切实改善患者的血脂水平,减轻神经功能缺损程度,提高日常生活活动能力和生活质量,值得临床推广。Objective To evaluate the clinical efficacy of combined administration of rosuvastatin calcium tablets and aspirin enteric-coated tablets for patients with ischemic cerebrovascular disease.Methods A total of 218 patients with ischemic cerebrovascular disease admitted to the Third Staff Hospital of Baotou Steel Group were selected and divided into the reference group(n=109)and the analysis group(n=109)using a single-blind method to receive administration of aspirin enteric-coated tablets and combined administration of aspirin enteric-coated tablets and rosuvastatin,respectively,and the clinical efficacy was compared between the two groups.The study lasted from January 2021 to December 2022.Results The blood liquid level in the analysis group were better than those in the reference group,with a statistically significant difference(P<0.05).The activities of the national institute of health stroke scale(NIHSS)score,Barthel index,the MOS item short form health survey(SF-36)score,and treatment total effectiveness rate of the analysis group were higher than those of the reference group,with statistically significant differences(P<0.05).Conclusion For patients with ischemic cerebrovascular disease,the combined administration of rosuvastatin calcium tablets and aspirin enteric-coated tablets has a definite overall treatment effect,can effectively improve the patient’s blood lipid levels,reduce the degree of neurological deficits,improve daily living activities and quality of life,and is worth promoting in the clinic.

关 键 词：缺血性脑血管病 他汀类药物 抗血小板聚集药物 瑞舒伐他汀 

分 类 号：R743.3[医药卫生—神经病学与精神病学]