嗜酸细胞性胃肠炎1例并文献复习  

A case of eosinophilic gastroenteritis and literature review

作　　者：李丽斌[1] LI Libin(Department of Gastroenterology,the Second Affiliated Hospital of Fujian Medical University,Fujian,Quanzhou 362000,China)

机构地区：[1]福建医科大学附属第二医院消化内科,福建泉州362000

出　　处：《中国医药科学》2024年第6期185-189,共5页China Medicine And Pharmacy

基　　金：福建省自然科学基金项目(2023J01733)。

摘　　要：嗜酸细胞性胃肠炎(EGE)是一种罕见的慢性消化道疾病,以胃肠组织中嗜酸性粒细胞浸润为特征,其病因及发病机制不明。目前认为其机制可能是由免疫球蛋白E(IgE)介导的Ⅰ型超敏反应和2型辅助性T细胞(Th2)介导的免疫反应共同完成。该病临床表现多种多样,可表现为腹痛、腹泻、呕吐甚至是腹水,可伴或不伴外周血嗜酸性粒细胞升高。由于该病的临床表现、辅助检查等缺乏特异性,病理诊断标准不规范,临床诊断较困难。本文报道1例嗜酸粒细胞性胃肠炎,以期提高临床医师对该病的认识。Eosinophilic gastroenteritis(EGE)is a rare chronic gastrointestinal disease characterized by infiltration of eosinophils in the gastrointestinal tissue.Its etiology and pathogenesis are unknown.At present,it is believed that its mechanism may be a combination of type I hypersensitivity mediated by immunoglobulin E(IgE)and immune response mediated by type 2 helper T cells(Th2).The clinical manifestations of this disease are diverse,including abdominal pain,diarrhea,vomiting,and even ascites,with or without elevated peripheral blood eosinophils.Due to the lack of specificity in clinical manifestations and auxiliary examinations,pathological diagnostic standards are still not standardized,and clinical diagnosis is still difficult.This article reports a case of eosinophilic gastroenteritis,in order to enhance clinical physicians’understanding of the disease.

关 键 词：嗜酸细胞性胃肠炎 临床表现 诊断 治疗 

分 类 号：R57[医药卫生—消化系统]