5344例体检者HP感染的分布特征及与肝功、血糖、血脂的相关性分析  

The distribution characteristics of Helicobacter pylori infection in 5344 Physical examination persons and its correlation with liver function,blood glucose,blood lipids

作　　者：张艳美 迟小伟[1] 柳卫芳[1] 卢晓荷 ZHANG Yan-mei;CHI Xiao-wei;LIU Wei-fang(Department of Clinical Laboratory,the Affiliated Hospital of Shandong University of Traditional Chinase Medicine,Shandong Jinan 250014)

机构地区：[1]山东中医药大学附属医院检验科,山东济南250014

出　　处：《医学检验与临床》2024年第2期23-27,共5页Medical Laboratory Science and Clinics

摘　　要：目的:探究济南地区人群幽门螺杆菌的感染状况以及幽门螺杆菌感染与肝功、血糖、血脂的相关性,为临床诊断和治疗幽门螺杆菌感染提供参考依据。方法:收集2022年9月1日一2022年12月31日在山东中医药大学附属医院进行健康体检的5344例体检者的基本信息以及幽门螺杆菌抗体检测结果和生化指标。采用SPSS22.0进行数据的统计学分析。结果:幽门螺杆菌感染阳性率为39.85%,其中以I型幽门螺杆菌感染为主,达到24.94%;幽门螺杆菌感染与性别差异无关;不同年龄段的幽门螺杆菌感染差异有统计学意义,II型HP组中中年人群所占比例高于阴性对照组和I型HP组,而青年人群所占比例低于其余两组;幽门螺杆菌感染者的ALB、GLU、TG、CHOL、LDL-C水平与阴性对照者比较差异有统计学意义,I型HP组和I型HP组的ALB水平均低于阴性对照组,而GLU、TG、CHOL、LDL-C水平均高于阴性对照组;HDL-C水平在不同组间差异无统计学意义。结论:幽门螺杆菌感染以I型为主,感染情况与性别差异无明显相关性,幽门螺杆菌感染人群的ALB水平低于健康人群,而GLU、TG、CHOL、LDL-C水平高于健康人群,I型与II型幽门螺杆菌感染人群间的ALB、GLU、TG、CHOL、HDL-C、LDL-C水平无明显差异。Objective:To explore the infection status of Helicobacter pylori in Jinan and the correlation between H.pylori infection and liver function,blood glucose,blood lipids,and provide reference for the clinical diagnosis and treatment.Methods:A total of 5344 patients who underwent physical examination in the Affiliated Hospital of Shandong University of Traditional Chinase Medicine from September 1,2022 to December 31,2022 were studied.We collected the patients basic information,H.pylori antibody detection results and biochemical results.SPSS22.0 was used for statistical analysis of the data.Results:The positive rate of H.pylori infection was 39.85%,of which the type I was the main infection type,reaching 24.94%.The infection of H.pylori was not associated with sex difference.The difference of H.pylori infection in different age groups was significant.The proportion of middle-aged people in the type II HP group was higher than that in the negative control group and typeIHP group,while the proportion ofyoung people was lower than in the other two groups.The levels ofALB,GLU,TG,CHOL,LDL-Cin patients infected with H Pylori were statistically significantly different from those in the negative control.The level of ALB in the type I HP group and type II HP group was lower than that in the negative control group,while the levels of GLU,TG,CHOL,and LDL-C were higher than those in the negative control group.The level of HDL-C was not statistically significant between different groups.Conclusion:The type I was the main infection type of H.pylori The infection status was not associated with sex difference.The level ofALB in people infected with H pylori was lower than that in healthy people,while the levels of GLU,TG,CHOL,LDL-C were higher than those in healthy people.There were no significant difference in the levels of ALB,GLU,TG,CHOL,HDL-C,and LDL-C between people infected with the type I H.pylori and the type II H.pylori.

关 键 词：幽门螺杆菌 抗体 肝功 血糖 血脂 

分 类 号：R573[医药卫生—消化系统]