情绪任务在情感障碍中的近红外脑功能成像研究进展  

Advances in near-infrared brain functional imaging of emotional tasks in affective disorder

作　　者：郭灿 杨春霞[1] 孙宁[1] GUO Can;YANG Chunxia;SUN Ning(Department of Mental Health,the First Hospital of Shanxi Medical University,Taiyuan 030001,China)

机构地区：[1]山西医科大学第一医院精神卫生科,太原030001 [2]山西医科大学人文社会科学学院

出　　处：《中国神经精神疾病杂志》2024年第1期54-59,共6页Chinese Journal of Nervous and Mental Diseases

基　　金：山西省自然科学基金(编号:20210302123257,20210302123251)

摘　　要：情绪任务(emotional task)是研究情感障碍(affective disorder)注意偏向和情感功能中的主要手段之一。基于情绪任务下功能性近红外光谱成像(functional near-infrared spectroscopy,fNIRS)的相关研究表明,面部情绪识别任务、情绪stroop任务以及情绪诱导任务结合fNIRS技术在情感障碍诊断、治疗中具有临床价值,情感障碍患者注意功能和情绪处理存在的缺陷与左侧前额叶皮质异常激活有关,特别是脑激活模式的差异与抑郁障碍患者抑郁症状有关。使用fNIRS研究情绪任务的未来方向重点在联合多种神经影像学手段进行大样本纵向队列研究以获得更加客观的诊疗依据,以及对比不同情绪刺激材料所激活区域的差异。Emotional task is one of the main methods to study the attention bias and emotional function of affective disorder.Functional near-infrared spectroscopy(fNIRS)studies based on emotional tasks in patients with affective disorders have shown that facial emotion recognition task,the emotional stroop effect,and the emotion induction task combined with fNIRS technology have clinical value in the diagnosis and treatment of affective disorders.The defects of attention function and emotional processing in patients with affective disorders are related to abnormal activation of the left prefrontal cortex,especially the differences in brain activation patterns are related to depressive symptoms in patients with depressive disorders.The future direction of using fNIRS to study emotional tasks is to combine a variety of neuroimaging methods to conduct large-sample longitudinal cohort studies to obtain more objective bases for diagnosis and treatment,and to compare the differences in activation areas of different emotional stimulation materials.

关 键 词：抑郁障碍 双相障碍 情感症状 近红外脑功能成像 额颞叶 氧合血红蛋白 情绪任务 

分 类 号：R749.4[医药卫生—神经病学与精神病学]