多样性腭部疾病数据的临床预判关键点  

Key points of clinical prediction based on diverse palate disease data

作　　者：胡芸 聂敏海 刘耀强[4] 何儒雅 刘旭倩 HU Yun;NIE Minhai;LIU Yaoqiang;HE Ruya;LIU Xuqian(Department of Periodontics and Oral Mucosal Diseases,The Affiliated Stomatology Hospital,Southwest Medical University,Luzhou 646000,China;Luzhou Key Laborator of Oral and Maxillofacial Reconstruction and Regeneration,,Luzhou 646000,China;Institute of Stomatology,Southwest Medical University,Luzhou 646000,China;Department of Oral and Maxillofacial Surgery,The Second Hospital of Hebei Medical University,Shijiazhuang 050000,China)

机构地区：[1]西南医科大学附属口腔医院牙周黏膜病科,泸州646000 [2]口颌面修复重建和再生泸州市重点实验室,泸州646000 [3]西南医科大学口腔医学院研究所,泸州646000 [4]河北医科大学第二医院口腔颌面外科,石家庄050000

出　　处：《西南医科大学学报》2024年第2期152-156,共5页Journal of Southwest Medical University

基　　金：四川省科学技术厅科技计划项目(2022NSFSC0716);泸州市科技计划项目(2023RCX171);西南医科大学应用基础重点项目(2021ZKZD010);导师组能力提升资助项目(2023DS12)。

摘　　要：目的研究多样性腭部疾病数据的临床预判关键点。方法共纳入335例腭部疾病患者,来源于河北医科大学第二医院(n=245)与西南医科大学附属医院(n=90)。根据性别、年龄、发病部位、病理类型和组织学来源等抽取数据,依次分组,探讨腭部疾病关联各参数后的类型及特征分布,找到腭部疾病多样性临床预判的指导性关键点。结果腭部恶性肿瘤好发于男性,以口腔黏膜上皮源性肿瘤为主,鳞癌最多;良性肿瘤好发于女性,以唾液腺上皮源性肿瘤为主,多形性腺瘤最多。腭部疾病好发年龄区间为41~60岁,其中腭部良性肿瘤好发年龄区间为61~80岁,腭部恶性肿瘤好发年龄区间为21~60岁。腭部囊肿好发于硬腭,而其他腭部疾病均在软硬腭交界区高发。腭部良性肿瘤组织病理学以唾液腺上皮源性肿瘤来源为主,而腭部恶性肿瘤则以口腔黏膜上皮源性肿瘤来源为主。结论通过腭部疾病关联性别比例、年龄区间、好发区域、病理类型,寻找到多样性腭部疾病的临床预判关键点,进而预判腭部疾病方向,降低误诊率,为患者争取最佳治疗时机,提高患者的生存预后。Objective Multifarious palatal diseases were concluded in the retrospective study in order to provide the key point of prediction for clinical diagnosis of palate diseases.Methods A total of 335 patients with palatal diseases were concluded,includ-ing 245 patients in the Second Hospital of Hebei Medical University(n=245)and 90 patients in the Affiliated Hospital of Southwest Medical University(n=90).The data collected included gender,age,diseased parts,pathological type and histological origin.The groups were divided in turn based on the characteristic of palatal diseases,and the correlation was analyzed.Results Malignant tu-mors in the palate were more common in males,primarily originating from oral mucosal epithelium,with squamous cell carcinoma being the most prevalent.Benign tumors were more common in females,primarily originating from salivary epithelium,with pleomorphic ad-enoma being the most frequent.The age group with a higher incidence of palatal diseases was 41 to 60 years old.Within this range,be-nign tumors of the palate were more common among individuals aged 61 to 80,while malignant tumors of the palate were more common in the age group of 21 to 60.For pathological type,cysts often occurred on the hard palate,whereas other diseases tended to be on the junction of soft and hard palate.As for histological origin,most palatal benign tumors were originating from salivary epithelium,whereas most palatal malignant tumors were oral epithelium.Conclusion By analyzing the correlation between gender ratios,age ranges,preva-lent regions,and pathological types associated with palatal diseases,diverse clinical predictive factors for palatal diseases were identi-fied,which aimed to anticipate the direction of palatal diseases,reduce misdiagnosis rates,secure the best treatment timing for patients,and improve their prognosis for survival.

关 键 词：腭部疾病 性别比例 年龄区间 病变部位 病理类型 腭部肿瘤 组织学来源 

分 类 号：R780.1[医药卫生—口腔医学]