重视PET成像在帕金森病认知功能障碍早期诊断的价值  

Pay Attention to the Application of PET Imaging in the Early Diagnosis of Cognitive Dysfunction in Parkinson's Disease

作　　者：卢洁[1] LU Jie(Department of Radiology and Nuclear Medicine,Xuanwu Hospital,Capital Medical University/Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics/Key Laboratory of Neurodegenerative Diseases,Ministry of Education,Beijing 100053,China)

机构地区：[1]首都医科大学宣武医院放射与核医学科,磁共振成像脑信息学北京市重点实验室,神经变性病教育部重点实验室,北京100053

出　　处：《中国医学影像学杂志》2024年第3期209-212,共4页Chinese Journal of Medical Imaging

基　　金：国家重点研发计划项目(2022YFC2406904)。

摘　　要：帕金森病(PD)是仅次于阿尔茨海默病的第二大神经退行性疾病,严重危害人们的生命健康,给社会和家庭带来巨大负担。PD认知功能障碍主要包括PD轻度认知损害和PD痴呆。随着不同PET靶向示踪剂的发展,目前PET成像技术已经成为评估PD患者认知功能障碍的重要分子影像手段,对早期诊断具有重要价值。Parkinson's disease(PD)is the second largest neurodegenerative disease,secondary to Alzheimer's disease,which seriously endangers people's life and health,and brings huge burden to society and family.Cognitive dysfunction in PD mainly includes mild cognitive impairment and dementia.With the development of different PET targeting tracers,PET imaging technology has become an important molecular imaging tool for assessment of cognitive dysfunction in PD patients,which is of great value for early diagnosis of PD with cognitive dysfunction.

关 键 词：帕金森病 认知障碍 正电子发射断层显像 诊断 

分 类 号：R742.5[医药卫生—神经病学与精神病学] R445.3[医药卫生—临床医学]