帕金森病心脏神经受体显像的研究进展  

Progress in Cardiac Neuroreceptor Imaging in Parkinson's Disease

作　　者：呼庚 白侠[2] HU Geng;BAI Xia(Department of Nuclear Medicine,the Affiliated Hospital of Inner Mongolia Medical University/Inner Mongolia Autonomous Region Key Laboratory of Molecular Imaging,Hohhot 010050,China)

机构地区：[1]内蒙古医科大学,内蒙古呼和浩特010110 [2]内蒙古医科大学附属医院核医学科,内蒙古自治区分子影像学重点实验室,内蒙古呼和浩特010050

出　　处：《中国医学影像学杂志》2024年第3期294-298,共5页Chinese Journal of Medical Imaging

基　　金：内蒙古自治区科技计划项目(2021GG0236)。

摘　　要：帕金森病(PD)作为一种神经退行性疾病,常伴有心脏自主神经系统功能异常,临床表现包括心律失常、血压波动、起搏器需要和心脏瓣膜功能异常等,这些变化可能对患者的生活质量和预后产生重要影响。因此,及早检测和监测PD患者的心脏自主神经受损非常重要,可以为患者提供合理的治疗和管理策略,以减轻心脏相关的症状和风险。心脏神经受体显像是一种可以直观显示心脏交感神经完整性和功能状态的方法,对评价心脏交感神经功能具有很高的灵敏度,对早期诊断PD至关重要。本文将重点介绍心脏神经受体显像剂在PD诊断方面的最新研究进展。Parkinson's disease(PD),as a neurodegenerative disorder,is often accompanied by dysfunction of the cardiac autonomic nervous system.Clinical manifestations include arrhythmias,blood pressure fluctuations,pacemaker dependency,and abnormalities in cardiac valve function.These changes can have a significant impact on the quality of life and prognosis of patients.Therefore,early detection and monitoring of cardiac autonomic dysfunction in PD patients is crucial and can provide appropriate treatment and management strategies to alleviate cardiac symptoms and risks.Cardiac sympathetic nerve receptor imaging is a method that can visually display the integrity and functional status of the cardiac sympathetic nervous system.It has high sensitivity for evaluating cardiac sympathetic nerve function,which is essential for early diagnosis of PD.This article focuses on the latest research progress in the use of cardiac sympathetic nerve receptor imaging agents for PD diagnosis.

关 键 词：帕金森病 临床诊断 心脏核素显像 交感神经系统 综述 

分 类 号：R742.5[医药卫生—神经病学与精神病学] R445[医药卫生—临床医学]