机构地区:[1]湖南中医药大学,长沙410208 [2]宁乡市中医医院 [3]湖南中医药大学第一附属医院
出 处:《中国中医骨伤科杂志》2024年第3期1-6,共6页Chinese Journal of Traditional Medical Traumatology & Orthopedics
基 金:国家自然科学基金项目(82174414,82274543);湖南中医药大学中医学一流学科开放基金重点课题(2021ZYX08);湖南省卫健委项目(20200442,20200440)。
摘 要:目的:观察改良骨牵引治疗技术对兔胫骨斜形骨折复位效果的影响,探讨对胫骨斜形骨折患者实施一种新的骨牵引方案的可能性。方法:选取体型和体重相近的家兔24只,通过截骨术进行胫骨斜形骨折造模,造模成功后随机分为对照组和观察组各12只,对照组用传统轴向骨牵引技术治疗,观察组用改良骨牵引技术治疗,均采取持续14 d的仰卧位牵引,观察牵引前后两组家兔的骨折复位效果、伤肢周径及血清中血管内皮生长因子(VEGF)、白细胞介素6(IL-6)的含量改变。结果:两组模型兔胫骨骨折复位有效率,观察组(83.33%)大于对照组(75.00%),差异有统计学意义(P=0.002);两组模型兔牵引第1,3,5,7,14天的伤肢周径,观察组(14.38,12.95,11.49,9.59,9.26 cm)小于对照组(14.66,13.84,12.68,11.70,11.29 cm),两组家兔在牵引第1,3,5,7,14天后的伤肢周径比较差异有统计学意义(P<0.05);两组模型兔牵引前后的血清中VEGF、IL-6显著改善,差异有统计学意义(P<0.05)。结论:改良骨牵引技术治疗胫骨斜形骨折复位疗效显著,治疗后骨折复位效果优于传统轴向骨牵引技术,治疗后伤肢肿胀周径小于传统轴向骨牵引技术,可作为治疗胫骨骨折新的有效牵引方法。Objective:To investigate the efficacy of modified bone traction therapy on the reduction of oblique tibial fractures in rabbits,and to assess the feasibility of applying an alternative bone traction scheme in clinical practice for patients with oblique fractures.Methods:A total of 24 white rabbits with similar body size and weight were chosen to perform diagonal tibial fracture modeling by osteotomy,and after successful modeling,they were randomly divided into the control group(12 cases) and the observation group(12 cases),in which the control group received traditional axial bone traction technology and the observation group received modified bone traction.They all sat in supine traction for 14 d,and the fracture reduction effect,injured limb circumference,and vascular endothelial growth factor(VEGF) and interleukin-6(IL-6) values in serum of the two groups of rabbits before and after traction were measured.Results:The reduction rate of the two groups:the reduction effective rate of the observation group was 83.33% and was higher than that of the control group of 75.00%(P<0.05).The circumference of injured limbs on the 1st,3rd,5th,7th and 14th day after traction in the two groups:the circumference of injured limbs in the observation group were 14.38,12.95,11.49,9.59,9.26 cm,respectively,which was smaller than those of the control group(14.66,13.84,12.68,11.70,11.29 cm),and there was significant difference in the circumference of injured limbs between the two groups on the 1st,3rd,5th,7th and 14th day after traction(P<0.05).The VEGF and IL-6 levels in serum of the two groups of rabbits before and after traction were significantly improved,and the difference was statistically significant(P<0.05).Conclusion:Modified bone traction has a significant efficacy in reducing oblique tibial fractures;its reduction efficacy is better than that of traditional axial bone traction,and the swelling circumference of the injured limb after modified bone traction is smaller than that of traditional axial bone traction,which indica
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