认知融合联合12针系统经会阴前列腺穿刺活检在日间手术模式中的应用  

Application of cognitive fusion combined with 12-core systematic transperineal prostate biopsy in daytime operation mode

作　　者：杨睿 孙佳宁[1] 蒋晓舻 欧阳奎 张峰 赵红伟[2] YANG Rui;SUN Jianing;JIANG Xiaolu;OU Yangkui;ZHANG Feng;ZHAO Hongwei(School of Clinical Medicine,Weifang Medical University,Weifang,Shandong,261053,China;Department of Urology,Yantai Yuhuangding Hospital Affiliated to Qingdao University;Binzhou Medical University)

机构地区：[1]潍坊医学院临床医学院,山东潍坊261053 [2]青岛大学附属烟台毓璜顶医院泌尿外科 [3]滨州医学院

出　　处：《临床泌尿外科杂志》2024年第2期111-114,119,共5页Journal of Clinical Urology

基　　金：国家自然科学基金(No:81972376);山东省泰山学者资助基金资助计划项目(No:tsqn202211379);2023年山东省抗体药物创新创业共同体重大科技项目(No:005)。

摘　　要：目的:探讨认知融合联合12针系统经会阴前列腺穿刺活检在日间手术模式下开展的安全性和有效性。方法:回顾性收集2019年6月—2022年8月于青岛大学附属烟台毓璜顶医院在日间手术模式下行经会阴前列腺认知融合穿刺活检的489例患者的临床病理特征,观察前列腺癌(prostate cancer,PCa)检出率、手术时间、疼痛耐受度、并发症等情况。结果:共检出PCa261(53.37%)例,有临床意义前列腺癌(clinically significant prostate cancer,csPCa)占78.93%(206/261)。系统穿刺与认知融合穿刺的PCa总检出率差异无统计学意义(47.03%vs 44.17%,230例vs216例,P=0.135),认知融合穿刺较系统穿刺检出更多csPCa(36.61%vs32.92%,179例vs 161例,P<0.001)。平均手术时间(8.92±0.98)min;视觉模拟评分(visual analogue scale,VAS)平均(2.50±1.16)分;术后并发症发生率为10.02%,其中急性尿潴留5例,血尿35例,发热9例,无脓毒症发生,经对症处理后均好转。结论:认知融合联合12针系统经会阴前列腺穿刺活检在日间手术模式下开展是安全有效的。Objective:To evaluate the safety and efficacy of cognitive fusion combined with 12-core systematic transperineal prostate biopsy in daytime operation mode.Methods:The clinical data of 489 patients who underwent transperineal cognitive fusion prostate biopsy in daytime operation mode in Yantai Yuhuangding Hospital were analyzed retrospectively from June 2019 to August 2022.Prostate cancer detection rate,operation time,hospital stay,visual analogue scale,and complications were recorded.Results:Prostate cancer was detected in 261(53.37%)patients and cancer detection rates for clinically significant prostate cancer was 78.93%(206/261).There was no significant difference in the total PCa detection rate between systemic and cognitive fusion biopsy(47.03%vs 44.17%,230 cases vs 216 cases,P=0.135),and more clinically significant prostate cancers were detected by cognitive fusion biopsy(36.61%vs 32.92%,179 cases vs 161 cases,P<0.001).The average operation time was(8.92±0.98)minutes.The average visual analogue scale was 2.50±1.16(0-6).Complication incidence was 10.02%,including urinary retention(5 patients),hematuria(35 patients)and fever(9 patients).No patients had sepsis and all complications were improved after treatment.Conclusion:Cognitive fusion combined with 12-core systematic transperineal prostate biopsy in daytime operation mode was safe and effective.

关 键 词：经会阴 前列腺活检 日间手术 认知融合 

分 类 号：R737.25[医药卫生—肿瘤]