基于玄府理论探讨脑-肠轴生理功能和病理  

Exploration on the physiological function and pathology of brain-gut axis based on Xuanfu theory

作　　者：郝琳瑶 李双阳 王饶琼 唐红梅 王明杰 白雪 HAO Linyao;LI Shuangyang;WANG Raoqiong;TANG Hongmei;WANG Mingjie;BAI Xue(Southwest Medical University,Luzhou 646000,China;The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University,Luzhou 646000,China)

机构地区：[1]西南医科大学,泸州646000 [2]西南医科大学附属中医医院,泸州646000

出　　处：《中华中医药杂志》2024年第3期1437-1440,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家中医药管理局中医药创新团队及人才支持计划项目(No.ZYYCXTD-C-202207);四川省科技计划项目(No.2020YJ0437);泸州市科技计划项目(No.2020-SYF-30);西南医科大学科研项目(No.2020ZRQNA037);西南医科大学附属中医医院创新团队(No.2022-CXTD-05)。

摘　　要：脑-肠轴理论提出大脑与肠道之间存在双向通讯,涉及神经、内分泌、免疫等系统,在机体生理病理机制中均发挥重要调节作用。“玄府”是中医理论对人体结构最微观的结构认识,相较于传统中医学理论中的阴阳、五行等宏观学说,可从微观层面解析人的生理功能和疾病机理。文章基于脑、肠结构和功能的共同之处,从玄府理论认识脑-肠轴生理特性、病理变化,拓展玄府理论内涵,可为中医药防治脑病提供新思路。The brain-gut axis theory proposes that there is a bidirectional communication between the brain and the intestine,involving neural,endocrine and immune systems,which all play an important regulatory role in the physiological and pathological mechanisms of the body.‘Xuanfu'is the most microscopic understanding of the structure of the human body in traditional Chinese medicine theory.Compared with the macroscopic theories of yin and yang and the five elements in traditional Chinese medicine,it can analyze the physiological functions and disease mechanisms of human beings at the microscopic level.Based on the commonality of brain and intestine structures and functions,this paper understands the physiological characteristics and pathological changes of the brain-gut axis from the Xuanfu theory,and expands the connotation of Xuanfu theory,which can provide new ideas for the prevention and treatment of brain diseases in Chinese medicine.

关 键 词：玄府理论 脑肠相通 脑-肠轴 

分 类 号：R223[医药卫生—中医基础理论] R228[医药卫生—中医学]