Non-pharmacological interventions for diabetic peripheral neuropathy:Are we winning the battle?  

作　　者：Dania Blaibel Cornelius James Fernandez Joseph M Pappachan 

机构地区：[1]Department of Endocrinology and Metabolism,Lancashire Teaching Hospitals NHS Trust,Preston PR29HT,United Kingdom [2]Department of Endocrinology&Metabolism,Pilgrim Hospital,United Lincolnshire Hospitals NHS Trust,Boston PE219QS,United Kingdom [3]Faculty of Science,Manchester Metropolitan University,Manchester M156BH,United Kingdom [4]Faculty of Biology,Medicine&Health,The University of Manchester,Manchester M139PL,United Kingdom

出　　处：《World Journal of Diabetes》2024年第4期579-585,共7页世界糖尿病杂志（英文版）（电子版）

摘　　要：Despite the advent of relatively reliable modalities of diagnosing diabetic peripheral neuropathy(DPN),such as nerve conduction studies,there is still a knowledge gap about the pathophysiology,and thus limited available in-terventions for symptom control and curtailing disease progression.The pharma-cologic aspect of management is mainly centred on pain control,however,there are several important aspects of DPN such as loss of vibration sense,pressure sense,and proprioception which are associated with risks to lower limb health,which pharmacotherapy does not address.Furthermore,published evidence suggests non-pharmacologic interventions such as glycaemic control through dietary modification and exercise need to be combined with other measures such as psychotherapy,to reach a desired,however modest effect.Acupuncture is emerging as an important treatment modality for several chronic medical conditions including neuropathic and other pain syndromes.In their study published in the World Journal of Diabetes on the potential of acupuncture to reduce DPN symptoms and enhance nerve conduction parameters,Hoerder et al have been able to demonstrate that acupuncture improves sensory function and that this effect is likely sustained two months after treatment cessation.Although previous studies also support these findings,larger multi-center randomized control trials including a sham-controlled arm accounting for a placebo effect are required.Overall,given the satisfactory safety profile and the positive results found in these studies,it is likely that acupuncture may become an important aspect of the repertoire of effective DPN management.

关 键 词：Diabetic peripheral neuropathy Diabetes mellitus PHARMACOTHERAPY ACUPUNCTURE Neuropathic pain Nonpharmacological intervention 

分 类 号：R587.2[医药卫生—内分泌] R543.5[医药卫生—内科学]