急性白血病患者早期危重症概述  

An overview of early critical illness in patients with acute leukemia

作　　者：卢聪 吴耀辉[1] 胡俊斌[1] LU Cong;WU Yaohui;HU Junbin(Institute of Hematology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,430022,China)

机构地区：[1]华中科技大学同济医学院附属协和医院血液病研究所,武汉430022

出　　处：《临床血液学杂志》2024年第3期156-161,共6页Journal of Clinical Hematology

基　　金：院内培育基金(No:2022xhyn003)。

摘　　要：新诊断的急性白血病患者在早期即疾病确诊后的4周内危重症发生是影响疾病预后和患者长期生存的重要因素。早期危重症主要包括高白细胞血症、弥散性血管内凝血、呼吸窘迫综合征、肿瘤溶解综合征以及严重出血等,早期危重症未及时识别和处理,则很快会导致早期死亡的发生,从而抵消由于药物的普及和诊疗规范的推进带来的长期生存获益。对于急性白血病早期危重症患者,早期识别并了解这些危重症的临床表现和防治措施,积极处理相关并发症,有助于提高患者的生存率和改善预后。The presence of critical illness in patients with newly diagnosed acute leukemia within 4 weeks after diagnosis is a significant determinant of prognosis and long-term survival.Early critical illnesses mainly include hyperleukocytosis,disseminated intravascular coagulation,respiratory distress syndrome,tumor lysis syndrome,and severe bleeding.Failure to promptly recognize and treat early critical illness can rapidly lead to premature mortality,negating the benefits derived from drug advancements and improved diagnostic and treatment standards.Timely identification,comprehension of clinical manifestations,implementation of preventive measures,management of complications are pivotal for enhancing the survival rate and prognosis of patients.

关 键 词：急性白血病 早期 危重症 

分 类 号：R733.71[医药卫生—肿瘤]