高白细胞急性白血病常见近期并发症  

Common short-term complications of hyperleukocytic acute leukemia

作　　者：何文娟[1] 陈智超[1] 胡豫[1] HE Wenjuan;CHEN Zhichao;HU Yu(Institute of Hematology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,430022,China)

机构地区：[1]华中科技大学同济医学院附属协和医院血液病研究所,武汉430022

出　　处：《临床血液学杂志》2024年第3期205-209,共5页Journal of Clinical Hematology

摘　　要：高白细胞急性白血病为血液科危重症,早期死亡风险高,其具有独特的临床表现、流行病学特征及病理生理学机制。白细胞淤滞、肿瘤溶解综合征和弥散性血管内凝血是其常见的近期并发症,对于此类患者,应根据不同情况选择合适的治疗方案并进行密切监测以减少早期死亡风险,为后续治疗提供时机。Hyperleukocytic acute leukemia is a critical disease in the department of hematology with a high risk of early death.It has unique clinical manifestations,epidemiological characteristics and pathophysiological mechanisms.Leukostasis,tumor lysis syndrome and disseminated intravascular coagulation are common short-term complications.For such patients,appropriate treatment should be selected according to different conditions and close monitoring should be performed to reduce the risk of early death and provide time for subsequent treatment.

关 键 词：高白细胞血症 急性白血病 白细胞淤滞 肿瘤溶解综合征 弥散性血管内凝血 并发症 

分 类 号：R733.71[医药卫生—肿瘤]