基于体外光学质量测试设备的非球面人工晶状体光学性能评价  

Evaluation of optical performance of aspherical intraocular lens in vitro by optical bench

作　　者：谢丽暄 廖萱[1] 兰长骏 谭青青[1] 潘若琳 唐玉玲 秦苏云 王艳[1] Xie Lixuan;Liao Xuan;Lan Changjun;Tan Qingqing;Pan Ruolin;Tang Yuling;Qin Suyun;Wang Yan(Department of Ophthalmology,Affiliated Hospital of North Sichuan Medical College,Medical School of Ophthalmology&Optometry,North Sichuan Medical College,Nanchong 637000,China;Chengdu Eastern Aier Eye Hospital,Chengdu 610056,China)

机构地区：[1]川北医学院附属医院眼科、川北医学院眼视光医学院,南充637000 [2]成都东区爱尔眼科医院,成都610056

出　　处：《中华实验眼科杂志》2024年第3期240-247,共8页Chinese Journal Of Experimental Ophthalmology

基　　金：四川省医学科研课题(S21011)。

摘　　要：目的应用体外光学质量测试设备OptiSpheric IOL R&D比较2种具有相同负球差值的非球面人工晶状体(IOL)AcrySof IQ SN60WF和Proming A1-UV的光学性能。方法应用OptiSpheric IOL R&D设备,分别在球差为0μm(ISO-1)和+0.28μm(ISO-2)的模型角膜以及孔径为3.0和4.5 mm条件下对+20.0 D蓝光滤过型SN60WF和高次非球面设计的非蓝光滤过全像差补偿型A1-UV IOL进行光学性能评估。分别测量IOL居中,偏心0.3、0.5、0.7、0.9和1.1 mm,倾斜3°、5°、7°、9°和11°的调制传递函数(MTF)以及USAF 1951分辨率测试图。采用紫外可见分光光度计UV-3300测试IOL的光谱透射比。结果与A1-UV IOL相比,SN60WF对400~500 nm波长蓝光的光谱透射比明显降低,能明显减少蓝光透过。当孔径为3.0 mm时,居中位置的SN60WF和A1-UV在100 lp/mm空间频率时ISO-1角膜测量条件下MTF值分别为0.576和0.598,ISO-2角膜测量条件下MTF值分别为0.564和0.563;当孔径为4.5 mm时,ISO-1角膜测量条件下MTF值分别为0.238和0.404,ISO-2角膜测量条件下MTF值分别为0.438和0.339。在3.0 mm孔径下,100 lp/mm空间频率时ISO-1角膜测量条件下MTF值均较ISO-2角膜测量条件下升高;在ISO-1角膜测量条件下,A1-UV相比于SN60WF展现出更优越的光学质量,而在ISO-2角膜测量条件下,2种IOL的光学质量相似。在3.0 mm孔径下,偏心0.3 mm的SN60WF和A1-UV在100 lp/mm空间频率时ISO-1角膜测量条件下MTF值分别为0.414和0.571,ISO-2角膜测量条件下MTF值分别为0.438和0.512,倾斜3°的ISO-1角膜测量条件下MTF值分别为0.522和0.597,ISO-2角膜测量条件下MTF值分别为0.532和0.531,A1-UV在2种角膜测量条件下的MTF值和USAF分辨率测试图未发生显著改变。当IOL发生相同程度偏心或倾斜时,除4.5 mm孔径ISO-1角膜测量条件以外,A1-UV各空间频率的MTF值相较于SN60WF均下降。随着孔径的增大,IOL偏心或倾斜对MTF值和USAF分辨率测试图的影响更加显著。结论SN60WF IOL能有效滤过波长在4Objective To evaluate the optical performance of two aspheric intraocular lenses(IOL)AcrySof IQ SN60WF and Proming A1-UV with identical negative spherical aberration values,using the optical bench OptiSpheric IOL R&D through an in vitro study.Methods The optical performance of+20.0 D blue-light filtering SN60WF and monofocal high-order aspheric non blue-light filtering A1-UV IOL was evaluated through cornea models with the spherical aberration of 0μm(ISO-1)and+0.28μm(ISO-2)under apertures of 3.0 mm and 4.5 mm via the optical bench OptiSpheric IOL R&D.The modulation transfer function(MTF)and USAF 1951 resolution test chart were employed to measure the IOL with centering,decentration of 0.3,0.5,0.7,0.9 and 1.1 mm,as well as tilt of 3°,5°,7°,9°and 11°.The spectral transmittance of IOL was measured with the UV-3300 UV-VIS spectrophotometer.Results Compared with the A1-UV IOL,the spectral transmittance of SN60WF for blue light with wavelengths of 400-500 nm was significantly reduced,which effectively reduced the passage of blue light.At an aperture of 3.0 mm,the MTF values at 100 lp/mm spatial frequency for the centered SN60WF and A1-UV were 0.576 and 0.598 under ISO-1 corneal measurement conditions,0.564 and 0.563 under ISO-2 conditions.At an aperture of 4.5 mm,the MTF values were 0.238 and 0.404 under ISO-1 corneal measurement conditions,and 0.438 and 0.339 under ISO-2 conditions.The MTF values of A1-UV and SN60WF at 3.0 mm aperture and 100 lp/mm spatial frequency under ISO-1 corneal measurement conditions were larger than those under ISO-2 corneal measurement conditions.Under ISO-1 corneal measurement conditions with a 3.0 mm aperture,A1-UV had a better optical quality compared to SN60WF,whereas under ISO-2 corneal measurement conditions,the optical quality of both IOLs was similar.Under the 3.0 mm aperture,the MTF values of SN60WF and A1-UV at a decentration of 0.3 mm and 100 lp/mm spatial frequency were 0.414 and 0.571 under ISO-1 corneal measurement conditions,0.438 and 0.512 under ISO-2 corneal measureme

关 键 词：人工晶状体 光学性能 体外 偏心 倾斜 成像质量 

分 类 号：R77[医药卫生—眼科]