根尖切除及倒充填术治疗口腔颌面根尖囊肿的效果及复发率观察  

Observation on the effect and recurrence rate of apical resection and retrograde filling in the treatment of oral and maxillofacial apical cyst

作　　者：张俊 邓四海 詹骏 ZHANG Jun;DENG Sihai;ZHAN Jun(Department of Stomatology,Pingxiang People’s Hospital,Pingxiang,Jiangxi,337000,China;Department of Clinical Laboratory,Pingxiang Maternal and Child Health Care Hospital,Pingxiang,Jiangxi,337000,China)

机构地区：[1]萍乡市人民医院口腔科,江西萍乡337000 [2]萍乡市妇幼保健院检验科,江西萍乡337000

出　　处：《当代医学》2024年第1期10-14,共5页Contemporary Medicine

摘　　要：目的探讨根尖切除及倒充填术治疗口腔颌面根尖囊肿的效果及复发率。方法选取2019年5月至2021年12月于萍乡市人民医院口腔科就诊的80例口腔颌面根尖囊肿患者作为研究对象,依据随机数字表法分为观察组与对照组,每组40例。观察组行根尖切除及倒充填术治疗,对照组仅行根尖切除术治疗。比较两组炎症因子[肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-1β(IL-1β)、C反应蛋白(CRP)]水平、牙周健康情况[牙龈指数(GI)、牙菌斑指数(PLI)、牙周袋深度(PD)]、患牙对日常生活的影响程度、不良反应发生情况及复发率。结果治疗后1周,两组TNF-α、IL-6、IL-1β、CRP水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗后1周,两组GI、PLI、PD均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗后1周,观察组明显疼痛、进食不适、味觉衰退、干预生活评分及总分均低于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。治疗后1个月,两组复发率比较差异无统计学意义;治疗后3个月,观察组复发率低于对照组,差异有统计学意义(P<0.05)。结论根尖切除结合倒充填术对口腔颌面根尖囊肿的治疗效果显著,能有效抑制炎症因子水平,改善口腔环境的卫生,减轻患牙术后对日常生活的影响,降低术后患牙不良反应发生率及复发率,值得临床推广应用。Objective To explore the effect and recurrence rate of apical resection and retrograde filling in the treatment of oral and maxillofacial apical cyst.Methods 80 patients with oral and maxillofacial apical cysts in department of stomatology of Pingxiang People’s Hospital were selected from May 2019 to December 2021 as the research subjects,they were classified into the observation group and the control group according to the random number table method,with 40 cases in each group.The observation group was treated with apical resection and retrograde filling,while the control group only adopted apical resection.The levels of inflammatory factors(tumor necrosis factor-α[TNF-α],interleukin-6[IL-6],interleukin-1β[IL-1β],C-reactive protein[CRP]),periodontal health status(gingival index[GI],plaque index[PLI],periodontal pocket depth[PD]),influence of affected teeth on daily life,occurrence of adverse reactions and recurrence rate were compared between the two groups.Results At 1 week after treatment,the levels of TNF-α,IL-6,IL-1βand CRP of the two groups were lower than those before treatment,and the levels in observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).At 1 week after treatment,the GI,PLI and PD of the two groups were lower than those before treatment,and the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).At 1 week after treatment,the scores of obvious pain,eating discomfort,taste recession and intervention life and total score in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The incidence rates of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).There was no statistical significance in recurrence rate between the two groups at 1 month after treatment;at 3 months after treatment,the recurrence rate

关 键 词：根尖切除 根尖倒充填术 根尖囊肿 复发率 

分 类 号：R78[医药卫生—口腔医学]