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作 者:褚月波 马建婷[2] CHU Yue-bo;MA Jian-ting(School of Medicine,Ningbo University,Ningbo 315211;Yuyao People’s Hospital,Yuyao 315400)
机构地区:[1]宁波大学医学院,宁波315211 [2]余姚市人民医院,余姚315400
出 处:《生殖医学杂志》2024年第4期553-558,共6页Journal of Reproductive Medicine
基 金:浙江省中医药临床研究计划项目(2023ZL166)。
摘 要:子宫内膜异位症(EMs)是指具有生长功能的子宫内膜组织(腺体和间质)出现在子宫腔以外的其他部位。EMs是一种常见的妇科慢性疾病,发生在青少年(WHO定义10~19岁为青少年)的EMs称为青春期EMs,也称之为早发性EMs。相对于育龄期女性,青少年中的EMs真实患病率不详,诊断和治疗延迟现象严重,将影响远期生育能力。青春期EMs发病机制不明,目前尚无早期无创诊断方法及有效的疾病预防手段。本文通过对国内外青春期EMs高危因素相关文献复习及归纳总结,试图早期识别青春期EMs,或通过减少高危因素的暴露来控制甚至逆转疾病的进展,保护远期生育能力。Endometriosis(EMs)refers to the presence of endometrial tissue(glands and stroma)with growth function in other parts outside the uterine cavity.It is a common chronic gynecological disease among women.EMs that occurs in adolescence(WHO defines adolescence as the range of 10 to 19 years old)is called adolescent EMs,and it is also reported as early-onset endometriosis.Compared with the disease in women of childbearing age,the prevalence of adolescent EMs is unknown,the delayed diagnosis and treatment would seriously affect long-term fertility.The pathogenesis of adolescent EMs is unknown,and there is no early non-invasive diagnostic method or effective preventive method at present.This article summarizes the latest literature on high-risk factors of adolescent EMs in order to provide evidences to identify adolescent EMs early and to help control or even reverse the progression of the disease by reducing the exposure of high-risk factors,resulting in protecting the long-term fertility.
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