Wnt/β-catenin信号通路在癫痫疾病中的研究进展  

Research Progress on the Role of Wnt/β-Catenin Signaling Pathway in Epilepsy

作　　者：刘德英 雷芳 谢苗莹 李洁玉 零冬慧 刁丽梅[2] LIU Deying;LEI Fang;XIE Miaoying;LI Jieyu;LING Donghui;DIAO Limei(Guangxi University of Chinese Medicine,Nanning 530200,Guangxi,China;The First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530022,Guangxi,China)

机构地区：[1]广西中医药大学,广西南宁530200 [2]广西中医药大学第一附属医院,广西南宁530022

出　　处：《实用中医内科杂志》2024年第3期8-10,共3页Journal of Practical Traditional Chinese Internal Medicine

基　　金：国家自然科学基金资助项目(81960858);广西科技厅科技基地和人才专项(桂科AD22035908);广西中医脑病临床研究中心项目(桂科AD20238028);广西高等学校高水平创新团队及卓越学者计划项目(桂教人才[2020]6号)。

摘　　要：Wnt/β-catenin信号通路(Wnt经典信号通路)是目前Wnt信号通路中研究较为深入的一条分支,在癫痫的发生发展中扮演重要角色。为提高对Wnt/β-catenin信号通路与癫痫关系的重视,并为癫痫治疗提供新靶点,文章就Wnt/β-catenin信号通路与癫痫关系的研究进展作一综述。Wnt/β-catenin signaling pathway(Wnt classical signaling pathway)is a branch of Wnt signaling pathway that has been deeply studied,and it plays an important role in embryo development,organogenesis,epilepsy and other major events from drosophila to human.In order to raise peoples attention to the relationship between Wnt/β-catenin signaling pathway and epilepsy,and to provide new targets for epilepsy treatment,this paper reviewed the research progress of the relationship between Wnt/β-catenin signaling pathway and epilepsy.

关 键 词：WNT/Β-CATENIN信号通路 癫痫 研究进展 

分 类 号：R742.1[医药卫生—神经病学与精神病学]