宫颈脱落细胞特殊染色技术在宫颈癌筛查中的应用效果  

The application effect of special staining technology for cervical exfoliated cells in cervical cancer screening

作　　者：黄府清 蒋群 蔡辉英 周恒 丁微 张流 阳晓敏 Huang Fuqing;Jiang Qun;Cai Huiying;Zhou Heng;Ding Wei;Zhang Liu;Yang Xiaomin(Department of Gynecology Outpatient,Liuzhou Maternal and Child Health Hospital,Liuzhou 545001,China)

机构地区：[1]柳州市妇幼保健院妇科门诊,广西柳州545001

出　　处：《实用妇科内分泌电子杂志》2024年第2期111-113,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨宫颈脱落细胞特殊染色技术在宫颈癌筛查中的应用效果。方法选取本院妇科门诊101名宫颈癌筛查女性为研究对象,均进行液基薄层细胞(TCT)和宫颈脱落细胞特殊染色技术检查,以阴道镜下宫颈活检病理结果为金标准,比较两种检查方法的诊断效能。结果宫颈组织病理学检查显示阳性35例,阳性率为34.7%;TCT检查的敏感度为31.7%、特异度为61.0%、阳性预测值为54.3%、阴性预测值为37.9%、准确度为43.6%,低于宫颈脱落细胞特殊染色技术的46.5%、74.1%、57.1%、65.2%、62.3%。结论宫颈脱落细胞特殊染色技术为无损伤检查,具有便携性高、操作简单、检测快速、经济实用和不依赖病理医师等特点,适用于人群普查或检测技术设备相对落后的偏远地区宫颈癌普查,也适合基层医院宫颈癌普查。Objective To exploring the application effect of special staining techniques for cervical exfoliated cells in cervical cancer screening.Methods 101 women screened for cervical cancer in the gynecological outpatient department of our hospital were selected as the research subjects,all of whom underwent liquid based thin-layer cell(TCT)and special staining techniques for cervical exfoliated cells.The pathological results of cervical biopsy under colposcopy were used as the gold standard to compare the diagnostic efficacy of the two examination methods.Results The pathological examination of cervical tissue showed 35 positive cases,with a positive rate of 34.7%;The sensitivity of TcT examination was 31.7%,specificity was 61.0%,positive predictive value was 54.3%,negative predictive value was 37.9%,and accuracy was 43.6%,which was lower than the 46.5%,74.1%,57.1%,65.2%,and 62.3%of cervical exfoliated cell special staining techniques.Conclusion The special staining technique for cervical exfoliated cells is a non-invasive examination,with high portability,simple operation,fast detection,economic practicality,and no dependence on pathologists.It is suitable for population census or cervical cancer census in remote areas with relatively backward detection technology and equipment,as well as for cervical cancer census in grassroots hospitals.

关 键 词：宫颈癌 筛查 诊断 宫颈脱落细胞特殊染色技术 宫颈组织病理学 

分 类 号：R737.33[医药卫生—肿瘤]