肺腺癌的MSCT征象与胸内增大淋巴结的关系分析  

Relationship between MSCT signs of lung adenocarcinoma and enlarged intrathoracic lymph nodes

作　　者：曾丹丹[1] 朱峰正 李新 肖木芳 ZENG Dan-dan;ZHU Feng-zheng;LI Xin(Health Management Center,Xiaolan People Hospital of Zhongshan,Zhongshan Guangdong 528400,China;Department of Radiology,Xiaolan People Hospital of Zhongshan,Zhongshan Guangdong 528400,China;Department of Medical Oncology,Xiaolan People Hospital of Zhongshan,Zhongshan Guangdong 528400,China)

机构地区：[1]广东省中山市小榄人民医院健康管理中心全科,广东中山528400 [2]广东省中山市小榄人民医院放射科,广东中山528400 [3]广东省中山市小榄人民医院肿瘤内科,广东中山528400

出　　处：《临床和实验医学杂志》2024年第5期551-554,共4页Journal of Clinical and Experimental Medicine

基　　金：中山市科学技术局资助项目(编号:2021SYF01)。

摘　　要：目的分析肺腺癌的多层螺旋CT(MSCT)征象与胸内增大淋巴结的关系。方法回顾性收集2020年6月至2023年6月在广东省中山市小榄人民医院行MSCT检查的96例肺腺癌患者的病例资料,根据患者是否出现胸内增大淋巴结(淋巴结短径>1 cm)分为有胸内增大淋巴结组(n=72)和无胸内增大淋巴结组(n=24),比较两组患者病理特征、MSCT征象,Logistic回归分析MSCT征象(肿瘤强化、血管集束征、分叶征、毛刺征、胸膜凹陷征)与胸内增大淋巴结的关系。结果有无胸内增大淋巴结肺腺癌患者肿瘤大小以及分化程度比较,差异均有统计学意义(P<0.05)。有无胸内增大淋巴结肺腺癌患者MSCT征象(肿瘤强化、血管集束征、分叶征、毛刺征以及胸膜凹陷征)比较,差异均有统计学意义(P<0.05)。Logistic回归分析肿瘤大小、分化程度、肿瘤强化和毛刺征均与胸内增大淋巴结的关系有统计学意义(P<0.05),回归系数分别为2.866、3.108、3.317和3.343,肿瘤大小、肿瘤强化和毛刺征均与胸内增大淋巴结呈正相关,肿瘤越大、强化程度越高、出现毛刺征,则越有可能出现胸内增大淋巴结;肿瘤分化程度与胸内增大淋巴结呈负相关,肿瘤分化程度越低,则越有可能出现胸内增大淋巴结。结论肺腺癌的MSCT表现如肿瘤大小、分化程度、CT强化程度、毛刺征均是胸内淋巴结增大的重要影响因素。Objective To analyze the relationship between multi-slice spiral CT(MSCT)signs of lung adenocarcinoma and enlarged intrathoracic lymph nodes.Methods A retrospective analysis was performed on the case data of 96 patients with lung adenocarcinoma who underwent MSCT examination in Xiaolan People's Hospital of Zhongshan between June 2020 and June 2023.According to presence or absence of enlarged intrathoracic lymph nodes(short diameter>1 cm),they were divided into the enlargement group(n=72)and the non-enlargement group(n=24).The pathological characteristics and MSCT signs in the two groups were compared.The relationship between MSCT signs(tumor enhancement,vessel convergence sign,lobulation sign,spiculation sign,pleural indentation sign)and enlarged intrathoracic lymph nodes was analyzed by Logistic regression analysis.Results There were statistically significant differences in tumor size and differentiation degree between the enlargement group and the non-enlargement group(P<0.05).There were statistically significant differences in MSCT signs(tumor enhancement,vessel convergence sign,lobulation sign,spiculation sign,pleural indentation sign)between the enlargement group and the non-enlargement group(P<0.05).Logistic regression analysis showed that tumor size,differentiation degree,tumor enhancement and spiculation sign were significantly correlated with enlarged intrathoracic lymph nodes(regression coefficient=2.866,3.108,3.317,3.343;P<0.05).Tumor size,tumor enhancement and spiculation signwere positively correlated with enlarged intrathoracic lymph nodes.The incidence of enlarged intrathoracic lymph nodes was higher in patients with larger tumors,higher tumor enhancement degree and spiculation sign.The degree of tumor differentiation was negatively correlated with enlarged intrathoracic lymph nodes.The incidence of enlarged intrathoracic lymph nodes was higher in patients with lower tumor differentiation.Conclusion MSCT manifestations of lung adenocarcinoma(tumor size,differentiation degree,CT enhancement degree,s

关 键 词：肺腺癌 多层螺旋CT 征象 胸内增大淋巴结 

分 类 号：R734.2[医药卫生—肿瘤] R730.44[医药卫生—临床医学]