内镜下黏膜切除术治疗消化道无蒂息肉的临床价值分析  

Clinical Value of Endoscopic Mucosal Resection in the Treatment of Sessile Polyps of Digestive Tract

作　　者：吴淑瑞 陈章兴 WU Shurui;CHEN Zhangxing(Department of Gastroenterology,73rd Group Military Hospital of the Chinese People's Liberation Army,Xiamen,Fujian Province,361001 China)

机构地区：[1]中国人民解放军陆军第七十三集团军医院消化内科,福建厦门361001

出　　处：《中外医疗》2024年第3期51-54,共4页China & Foreign Medical Treatment

摘　　要：目的探讨采取内镜下黏膜切除术治疗消化道无蒂息肉的应用价值。方法方便选取2022年1月—2023年4月中国人民解放军陆军第七十三集团军医院收治的112例消化道无蒂息肉患者为研究对象,按照随机数表法分为观察组和对照组,每组56例。对照组采用常规内镜下高频电凝切除术,观察组采用内镜下黏膜切除术。比较两组患者围术期指标、手术切除效果、手术前后炎症因子指标水平、术后并发症发生情况。结果观察组围术期指标水平优于对照组,差异有统计学意义(P<0.05);观察组切除成功率为98.21%高于对照组的87.50%,差异有统计学意义(χ^(2)=4.846,P=0.028);两组术后1 d血清C反应蛋白、白细胞介素-6高于术前1 d,差异有统计学意义(P均<0.05);两组术后3 d血清C反应蛋白、白细胞介素-6均下降,且术后1、3 d观察组血清C反应蛋白、白细胞介素-6均低于对照组,差异有统计学意义(P均<0.05);观察组术后并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论应用内镜下黏膜切除术治疗消化道无蒂息肉,相较于传统应用高频电凝电切手段,能减少手术时间,减轻手术对于患者的创伤,便于加快患者术后恢复进程,能提高息肉切除效果,降低术后炎症因子水平,且术后并发症发生率低。Objective To investigate the application value of endoscopic mucosal resection in the treatment of sessile polyps of digestive tract.Methods A total of 112 patients with stemless polyps of digestive tract admitted to the 73rd Group Military Hospital of the Chinese People's Liberation Army from January 2022 to April 2023 were conveniently selected as the study objects and divided into observation group and control group according to random number table method,with 56 cases in each group.The control group underwent conventional endoscopic high-frequency electrocoagulation resection,and the observation group underwent endoscopic mucosal resection.Perioperative indexes,surgical resection effect,pre-and post-operative inflammatory factor indexes and postoperative complications were compared between the two groups.Results The perioperative level of the observation group was better than that of the control group,and the difference was statistically significant(P<0.05).The success rate of resection in observation group was 98.21%higher than that in control group(87.50%),and the difference was statistically significant(χ^(2)=4.846,P=0.028);serum C-reactive protein and interleukin-61 day after surgery of two groups were higher than those 1 day before surgery,and the differences were statistically significant(both P<0.05);serum C-reactive protein and interleukin-63 days after surgery of two groups were decreased,and serum C-reactive protein and interleukin-6 in the observation group were lower than those in the control group 1 and 3 days after surgery,and the differences were statistically significant(all P<0.05).The total incidence of postoperative complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Compared with the traditional application of high-frequency electrocoagulation and electroresection,endoscopic mucosal resection can reduce the operation time and reduce the trauma to patients.In this way,it is convenient to acceler

关 键 词：消化道无蒂息肉 内镜下黏膜切除术 炎症因子 

分 类 号：R735[医药卫生—肿瘤]