跟骨软骨母细胞瘤一例及文献复习  

A Case Report of Calcaneal Osteochondroblastoma and Review of the Literature

作　　者：吴佳倩 閤承治 黎清波 胡显锋 杜艳华[1] WU Jia-qian;GE Cheng-zhi;LI Qing-bo;HU Xian-feng;DU Yan-hua(Department of General Practice,Wuhan Fourth Hospital of Hubei Province,Wuhan 430030,Hubei Province,China;Department of General Practice,Wuhan Third Hospital of Hubei Province,Wuhan 430060,Hubei Province,China;Bone Tumor And Spinal Surgery,Wuhan Fourth Hospital of Hubei Province,Wuhan 430030,Hubei Province,China)

机构地区：[1]湖北省武汉市第四医院全科医学科,湖北武汉430030 [2]湖北省武汉市第三医院全科医学科,湖北武汉430060 [3]湖北省武汉市第四医院骨肿瘤与脊柱外科,湖北武汉430030

出　　处：《罕少疾病杂志》2024年第4期4-6,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的通过报道一例影像学表现不典型,病理报告提示细胞丰富伴坏死的跟骨软骨母细胞瘤结合文献复习,探讨其误诊原因及是否为恶性软骨母细胞瘤可能。方法分析1例软骨母细胞瘤病理提示细胞丰富伴坏死的诊疗过程并结合相关文献进行分析。结论本病例手术时可见肿瘤边界尚清楚,未突破骨皮质,肉眼未见明显坏死及变性组织,考虑其恶变及转移可能性极小。细胞坏死原因考虑可能是跟骨体积小,肿瘤细胞在有限空间增殖,导致其坏死。细胞丰富考虑肿瘤增殖迅速有一定侵袭周围组织及转移可能,经手术对瘤体完整切除,周围组织充分灭活及骨水泥填充后其可能性也极小。该患者经两年随访后肿瘤无复发转移,证明该治疗方法有效。且软骨母细胞瘤极少恶变,增殖丰富并不能证明其为恶性软骨母细胞瘤。Objective To investigate the etiology of misdiagnosis and the potential malignant chondroblastoma of the calcaneus by reporting a case with atypical imaging findings and a pathological report indicating abundant cells with necrosis.Methods A comprehensive analysis of the diagnostic and therapeutic process was conducted for a single case of chondroblastoma characterized by cellular abundance and necrosis,in conjunction with relevant literature.Conclusion In this particular case,the margins of the tumor were well-defined,the bone cortex remained intact,and there was no evidence of malignant transformation.The reason for cell necrosis may be the small size of calcaneus and the proliferation of tumor cells in limited space,which leads to necrosis.Considering the rapid proliferation of the tumor,it is possible to invade the surrounding tissue and metastasize to a certain extent.After complete resection of the tumor,adequate inactivation of the surrounding tissue and filling of bone cement,the possibility of this tumor is also very small.After two years of follow-up,the patient had no tumor recurrence and metastasis,which proved that the treatment was effective.Moreover,chondroblastoma rarely becomes malignant,and abundant proliferation does not prove that chondroblastoma is malignant.

关 键 词：软骨母细胞瘤 跟骨 影像学表现不典型 细胞丰富伴坏死。 

分 类 号：R73[医药卫生—肿瘤]