虾青素的功能及其微生物工程菌构建研究进展  

Research progress on the function of astaxanthin and construction of microbial engineering bacteria

作　　者：黄广文 黄明珠 刘斌 陈雪岚[1,2] HUANG Guangwen;HUANG Mingzhu;LIU Bin;CHEN Xuelan(College of Life Science,National Center for Freshwater Fish Processing,Jiangxi Normal University,Nanchang 330027,China;Health College,Jiangxi Normal University,Nanchang 330027,China)

机构地区：[1]江西师范大学生命科学学院,国家淡水鱼加工技术研发专业中心,江西南昌330027 [2]江西师范大学健康学院,江西南昌330027

出　　处：《食品与发酵工业》2024年第7期331-337,共7页Food and Fermentation Industries

基　　金：国家自然科学基金项目(32260014,31960014);江西省自然科学基金项目(20224BAB215004,20224BAB215005)。

摘　　要：虾青素是一种抗氧化能力超强的类胡萝卜素,在保健品、食品添加剂、化妆品、医药等方面具有广阔的市场需求。微生物生长速度快,生长需要的营养物质相对于虾青素来说非常便宜,因此科研工作者采用代谢工程手段构建工程菌来生产虾青素。该文综述虾青素的功能及其应用、虾青素来源、虾青素合成途径及利用合成生物学提高微生物积累虾青素的方法,以期为相关科研人员进一步高效合成虾青素提供思路。Astaxanthin,a carotenoid with strong antioxidant capacity,has a broad market demand in health care products,food additives,cosmetics,and medicine.The growth rate of microorganisms is fast,and the nutrients required for growth are very cheap compared with astaxanthin.Therefore,researchers have used metabolic engineering methods to construct engineered bacteria to produce astaxanthin.In this review,we summarize the functions and applications of astaxanthin,the sources of astaxanthin,the synthesis pathways of astaxanthin,and the methods to improve the accumulation of astaxanthin by microorganisms using synthetic biology,in order to provide ideas for further efficient production of astaxanthin by relevant researchers.

关 键 词：虾青素 微生物 代谢工程 

分 类 号：O629.4[理学—有机化学]