Helicobacter pylori isolated from gastric juice have higher pathogenic potential than biopsy isolates  

作　　者：Budhadev Baral Dharmendra Kashyap Nidhi Varshney Tarun Prakash Verma Ajay Kumar Jain Debi Chatterji Vinod Kumar Amit Mishra Awanish Kumar Hem Chandra Jha 

机构地区：[1]Infection Bioengineering Group,Department of Biosciences and Biomedical Engineering,Indian Institute of Technology Indore,Simrol,Indore,Madhya Pradesh 453552,India [2]Choithram Hospital and Research Center,Indore,Madhya Pradesh452014,India [3]Department of Metallurgy Engineering and Materials Science,Indian Institute of Technology Indore,Simrol,Indore,Madhya Pradesh 453552,India [4]Department of Bioscience&Bioengineering,Indian Institute of Technology Jodhpur,NH 65 Nagaur Road,Jodhpur District,Karwar,Rajasthan 342037,India [5]Department of Biotechnology,National Institute of Technology Raipur,GE Road,Raipur,Chhattisgarh 492010,India

出　　处：《Genes & Diseases》2024年第1期34-37,共4页基因与疾病（英文）

基　　金：funded by SERB,India(No.EMR/2017/001637).

摘　　要：Persistent gastritis induced by Helicobacter pylori(H.pylori)is the strongest known risk factor for gastric cancer(GC).H.pylori is prevalent in about 50%world's population,while it causes cancer in less than 2%of exposed individuals.1 Our studies found that H.pylori infection can induce oncogenic properties in AGS cells by deregulating multiple factors associated with the cell cycle,apoptosis,and other important events associated with cancer progression.

关 键 词：H.PYLORI PYLORI HELICOBACTER 

分 类 号：R573[医药卫生—消化系统]