肌少症与认知障碍相关性的研究进展  

Research advances on the correlation between sarcopenia and cognitive impairment

作　　者：张康睿 刘秋皖 吴君仓 Zhang Kangrui;Liu Qiuwan;Wu Juncang(Hefei Second People's Hospital Affiliated to Bengbu Medical College,Hefei 230011,China;Department of Neurology,Hefei Second People's Hospital,Hefei 23001l,China)

机构地区：[1]蚌埠医学院附属合肥市第二人民医院,合肥230011 [2]合肥市第二人民医院神经内科,合肥230011

出　　处：《中华老年医学杂志》2024年第4期534-537,共4页Chinese Journal of Geriatrics

摘　　要：肌少症是指随着年龄增长而出现的肌肉量和躯体功能减退。认知障碍是指记忆、学习、定向、理解、判断等能力的减弱或受损。肌少症和认知障碍是老龄化人口中最常见的两种残疾原因。已有文献表明两者之间存在相关性,识别肌少症和认知障碍的共同危险因素及潜在机制对开发针对性的干预措施有指导意义,从而减缓甚至逆转肌少症和某些形式的认知减退。尽管已经进行了大量研究来量化这两种疾病之间的联系,但广泛的系统回顾仍然有限。Sarcopenia refers to the loss of muscle mass and decline in somatic function with increasing age.Cognitive impairment is defined as a diminished or impaired ability associated with memory,learning,orientation,comprehension and judgement.Sarcopenia and cognitive impairment are the two most common causes of disability in the aging population.Existing literature suggests a correlation between the two and the identification of common risk factors and potential mechanisms for sarcopenia and cognitive impairment can guide the development of targeted interventions to slow or reverse sarcopenia and some forms of cognitive decline.Although a large number of studies have been conducted to quantify the link between the two disorders,extensive systematic reviews remain limited.

关 键 词：认知障碍 痴呆 肌少症 

分 类 号：R749.1[医药卫生—神经病学与精神病学]