植物次生代谢产物生物合成基因簇研究进展  

Research Progress on Plant Secondary Metabolite Biosyn-thetic Gene Clusters

作　　者：朱璐 袁冲 刘义飞 Lu Zhu;Chong Yuan;Yifei Liu(Hubei University of Chinese Medicine,Wuhan 430074,China)

机构地区：[1]湖北中医药大学,武汉430074

出　　处：《植物学报》2024年第1期134-143,共10页Chinese Bulletin of Botany

基　　金：国家自然科学基金(No.32270231);湖北省杰出青年基金(No.2019CFA097)。

摘　　要：植物产生的次生代谢产物为人类提供了丰富的药物、香料和工业原料。随着分子生物学和基因组学研究的快速发展,目前已解析了多种植物的次生代谢产物生物合成基因簇(BGCs)。这为我们快速获取目标产物的生物合成通路和发掘新颖的天然产物开辟了新路径。该文重点围绕植物次生代谢产物生物合成基因簇的定义和特点、基本结构模型与演化以及调控机制等进行综述,以期为相关研究提供理论依据和借鉴。The secondary metabolites produced by plants provide human beings with a wealth of pharmaceutical,perfume and industrial raw materials.With the rapid development of molecular biology and genomics research,the biosynthetic gene clusters(BGCs)of secondary metabolites of various plants have been analyzed,which opens a new path for us to quickly obtain the biosynthetic pathways of target products and discover novel natural products.This paper focuses on the definition and characteristics of plant secondary metabolite biosynthesis gene clusters,and its basic structural models,evolution and regulatory mechanisms,in order to provide theoretical basis and reference for related research.

关 键 词：次生代谢产物 生物合成基因簇 基因簇调控 基因簇特征 

分 类 号：Q943.2[生物学—植物学]