红藤汤加减灌肠治疗粘连性肠梗阻的临床疗效研究  

Clinical effect of modified enema with Hongteng decoction on adhesive intestinal obstruction

作　　者：肖喜风 夏琴琴 丁斌[1] XIAO Xifeng;XIA Qinqin;DING Bin(Department of Gastroenterology,Jiujiang First People′s Hospital,Jiujiang,Jiangxi 332000,China;Outpatient Department of Traditional Chinese Medicine,Jiujiang First People′s Hospital,Jiujiang,Jiangxi 332000,China)

机构地区：[1]江西省九江市第一人民医院消化内科,江西九江332000 [2]江西省九江市第一人民医院中医科门诊,江西九江332000

出　　处：《检验医学与临床》2024年第8期1049-1053,共5页Laboratory Medicine and Clinic

基　　金：江西省中医药管理局科技计划(2022B780)。

摘　　要：目的探讨红藤汤加减灌肠治疗粘连性肠梗阻的临床疗效。方法选取2022年9月至2023年4月该院收治的86例粘连性肠梗阻患者作为研究对象,采用随机数字表法分为试验组与对照组,每组43例。对照组给予常规西药治疗,试验组在对照组基础上加用红藤汤加减灌肠治疗。比较两组治疗前及治疗3、7 d后的中医证候积分,患者血液标本中性粒细胞/淋巴细胞(NLR),比较两组疗效及不良反应发生率,比较两组恢复时间(胃管留置时间、腹痛缓解时间、腹胀缓解时间、首次排气时间、自行排便时间、气液平面消失时间、住院时间)及研究周期内因肠梗阻总住院次数。结果试验组治疗总有效率(93.02%)明显高于对照组(76.74%),差异有统计学意义(χ^(2)=4.440,P=0.035)。重复测量方差分析结果显示,两组治疗前及治疗3、7 d后的中医证候积分存在组间效应、时间效应、组间与时间的交互效应(P<0.05)。试验组胃管留置时间、腹痛缓解时间、腹胀缓解时间、首次排气时间、自行排便时间、气液平面消失时间、住院时间均短于对照组(P<0.05);试验组研究周期内因肠梗阻总住院次数少于对照组(P<0.05)。重复测量方差分析结果显示,两组治疗前及治疗3、7 d后的NLR存在组间效应、时间效应、组间与时间的交互效应(P<0.05)。两组不良反应发生率比较,差异无统计学意义(χ2=0.387,P=0.534)。结论粘连性肠梗阻采用红藤汤加减灌肠治疗,能有效调节机体NLR,加快临床症状缓解,提高临床疗效。Objective To investigate the clinical efficacy of modified enema with Hongteng decoction in the treatment of adhesive intestinal obstruction.Methods A total of 86 patients with adhesive intestinal obstruction admitted to the hospital from September 2022 to April 2023 were selected as the research objects,and they were divided into the experimental group and the control group by random number table method,with 43 cases in each group.The control group was treated with conventional western medicine,and the experimental group was treated with enema of Hongteng decoction on the basis of the control group.The TCM syndrome score,neutrophil/lymphocyte ratio(NLR)of blood samples were compared between the two groups before treatment and 3 and 7 days after treatment.The curative effect and incidence of adverse reactions were compared between the two groups.The recovery time(gastric tube indwelling time,abdominal pain relief time,abdominal distension relief time,first exhaust time,self-defecation time,liquid-air level disappearance time,hospitalization time)and the total number of hospitalization due to intestinal obstruction during the study period were compared between the two groups.Results The total effective rate of the experimental group(93.02%)was significantly higher than that of the control group(76.74%),the difference was statistically significant(χ^(2)=4.440,P=0.035).The results of repeated measures analysis of variance showed that there were between-group effects,time effects and interaction effects between groups and time in the TCM syndrome scores of the two groups before treatment,3 d and 7 d after treatment(P<0.05).The gastric tube indwelling time,abdominal pain relief time,abdominal distension relief time,first exhaust time,self-defecation time,liquid-air level disappearance time and the hospitalization time in the experimental group were shorter than those in the control group(P<0.05).The total number of hospitalization due to intestinal obstruction in the experimental group during the study period was les

关 键 词：粘连性肠梗阻 红藤汤 中药灌肠法 中医证候 临床疗效 

分 类 号：R574.2[医药卫生—消化系统]